Imagine you want to get rich by genetically engineering
Last updated: 3/25/2023
Imagine you want to get rich by genetically engineering tobacco plants to produce cann insert the genes for each of the enzymes in the hypothetical CBD synthesis pathway Let s just say that the first step the pathway is conversion of Acetyl CoA to the compound Malonyl CoA shown below This is purely hypothetical Imagine now that CBD is toxic at very high concentrations What would be the best way to synthesize CBD but to turn off its production before it reaches toxic concentrations and so that Acetyl CoA can be conserved for other processes Shown below is the hypothetical pathway I I2 and I3 are the intermediates in the pathway Enzymes 1 5 E1 E5 catalyze each reaction in the order in which they appear Acetyl CoA E1 Malonyl CoA E2 E3 E5 1 1 13 12 Allosteric inhibition of Enzyme 1 by Acetyl CoA Allosteric activation of E1 by Acetyl CoA O Allosteric inhibition of Enzyme 5 by CBD O Allosteric inhibition of Enzyme 1 by Malonyl CoA ition of Enzyme 1 by CBD E4 CBD