Which of the following best explains why echinocandins a

Last updated: 4/4/2023

Which of the following best explains why echinocandins a class of antifungal drugs are selectively toxic to fungal cells but not human cells Echinocandins target synthesis of ergosterol which is a central structure of the fungal cell membrane and humans contain cholesterol instead of ergosterol in their cell membranes Echinocandins bind to ergosterol in the cell membranes of fungi causing pores to form in their cell membranes and humans contain cholesterol instead of ergosterol in their cell membranes Echinocandins inhibit the function of fungal ribosomes which have a different prokaryotic structure compared to the eukaryotic ribosomes of humans Echinocandins target synthesis of beta glucans which are central structures of fungal cell walls and humans do not have cell walls