Biomolecules Questions and Answers

Fat soluble vitamins have a greater risk for toxicity because they are not easily a excreted Ob converted Oc hydrolyzed d destroyed e absorbed

One difference between water soluble vitamins and fat soluble vitamins is that a water soluble vitamins need to be consumed more frequently than fat soluble vitamins Ob fat soluble vitamins outnumber water soluble vitamins Oc fat soluble vitamins are easier for the body to excrete Od fat soluble vitamins need to be consumed more frequently than water soluble vitamins e in large amounts water soluble vitamins can be more toxic than fat soluble vitamins

N tion 8 3 points anscript LING estion 3 hydrochloric acid aq sod estion 3 2 Choose the correspondin

What early European civilization lived in the highlighted area of the map A Minoans B Mycenaeans C Romans

3 Explain the justification Canada had for wanting to separate from Great Britain 4 Do you think Canada should have asked fo full independence or should stay a dominion

1 Where does the electron transport system and oxidative phosphorylation occur 2 What is the chemical reaction for cellular respiration What does each of the symbols represent

3 What is the main function of cellular respiration Cell respiration is accomplished by three successive processes List them in order 1 2 3

0 9 m v NaCl aqueous solution is considered to be isotonic to osmotic presseure of blood calculate its osmotic pressure at 37 C

1 Monomers building blocks are joined together to form polymers through a chemical reaction called by removing a molecule of Monomers are attached

6 Nucleic acids Fill in the table below Describe the structure What sugar does it contain List the 4 nitrogenous bases DNA RNA

4 Proteins What are two ways that proteins can be denatured

3 List the monomer for each macromolecule Polysaccharides Proteins Nucleic acids

METABOLISM customized Mark the checkbox for each statement depending upon the Pushing a ball up a hill A burning campfire Demolishing a skyscraper Baking a cake Spontaneous Requires the input of energy

METABOLISM Custome Co Drag and drop to match the terms w Portion of the enzyme where the substrat Alteration of enzyme function by the bind Organic molecule such as a vitamin that Inorganic ion such as magnesium that

GD METABOLISM customized Select the statement s that correctly describe s th ANTE The activation energy is the energy needed to jump The input of energy in a chemical reaction is needed The transition state is a very stable low energy state Heat energy is a common form of activation energy Catalysts such as enzymes are often used to lower Increasing temperatures of organisms will cause mo

Which of the following group or moiety cannot be found in the following molecule R O ZI FO HILIN O

The diagram below is a generic example of wha A B C D positive feedback O equilibrium catabolism

Which of the following would have O 0 1 M NaCl MW 58 g mol

If the pH of a solution is 7 5 what is th 14 07 5 5 5 7 5

Drag and drop the statements to their category of the processes which inhibit the action of an enzyme Competitive Inhibition Non Competitive Inhibition Denaturing All Non Competitive Inhibition and Denaturing Cooking egg white as it turns from opaque to white Making ceviche with lemon juice Cyanide binds to the active site of the enzyme Alters the shape of the active site A metabolite from a metabolic pathway binds to the allosteric site of the enzyme Alters the activity of the enzyme Blocks the active site of the enzyme

Drag and drop the terms to label the diagram depicting enzyme action Products Enzyme products complex Substrate Active site Enzyme substrate complex Enzyme changes shape slightly as substrate binds Products leaving active site of enzyme Substrate entering active site of enzyme

Drag and drop the terms to match with their descriptions to assess the understanding of enzymes Definition Alteration of the structure of an enzyme that inhibits its proper function Inhibiting of a metabolic pathway by an intermediate molecule produced during the pathway Describes the method by which the substrate interacts with the active site of the enzyme Molecule that is acted on by the enzymes IITI Term

Select the statement s which is are incorrect while describing enzyme compartmentalization Enzyme compartmentalization is a mechanism of regulating the activity of an enzyme Enzymes allowed to circulate freely in the cytoplasm may inappropriately catalyze chemical reactions Lysosomes spill their enzymes into the cytoplasm to catalyze chemical reactions Reactions involved in cellular respiration and photosynthesis occur in specific organelles increasing efficiency

Anabolic Pathway Catabolic Pathway Anabolic Pathway and Catabolic Pathway Breakdown reactions Assembly of glycerol and three fatty acids to produce a triglyceride Building a tower out of bricks with your little brother Synthesis rea Destroying the tower like Godzilla Production of ATP Uses enzymes Digestion of carbohydrates in the small intestine

What is the major composition carbohydrate O protein

Baculovirus genomes are 133 9 kb long and encode over 150 genes This suggests that O 1 they have a small host range 2 their protein structures are very complex 3 their protein coats consist of very few types of protein subunits 4 their genetic material is DNA 5 their genetic material is RNA

1 a plasmid that gives bacteria the ability to exchange DNA with another bacterial cell 2 a plasmid that gives bacteria the ability to degrade toluene 3 a plasmid that can exist either autonomously in the cytoplasm or as part of a chromosome 4 a plasmid that can turn a bacteria that is harmless into a strain that can cause disease O5 a plasmid that can make bacterial cells resistant to antibiotics

Bacterial infections have become much more of a threat to human health due to which of the following 1 an increase in acquired antibiotic resistance by innocuous strains O 2 an increased use of antibiotics coupled with an increase in acquired antibiotic resistance by innocuous strains 3 horizontal transfer of pathogenicity 4 an increased use of antibiotics horizontal transfer of pathogenicity and an increase in acquired antibiotic resistance by innocuous strains 5 the increased use of antibiotics

8 Looking at this protein in MolView what is unusual about what you see What else is depicted along with the protein Can you do an approximate count of it them What does this tell you about the environment in which this protein must operate 9 points

2 Chain B PROTEIN BOVINE SEMINAL RIBONUCLEASE Accession 11BG B Provide the protein sequence 6 Looking at strand 104 110 and based on the information provided by this prediction is this strand located at the core or on the surface of the protein Justify your answer 7 How many cysteines does the protein have 10 How many of them are involved in disulfyde bonds Secondary Structure RePROF Solvent Accessibility RePROF Topology TMSEG Disordered Region Meta Disorder Relative B Value PROFbval Protein Binding ProNA DNA Binding ProNA RNA Binding ProNA Disulfide Bond DISULFIND Conservation ConSeq Secondary Structure RePROF Other Helx Strand Solvent Accessibility RePROF Exposed Buried Topology TMSEG Disordered Region Meta Disorden Disordered Region Relative B Value PROFbval 00 30 Low 31 70 Intermediate 71 99 1 Protein Binding ProNA Protein Binding R1 00 33 Protein Binding R 34 66 ONA Binding ProNA RNA Binding PONA Disulfide Bond DISULFINDE Disulfide Bond III Conservation ConSea Conservation Score 1 3 Low Conservation Score 4 6 CO I 7777 1 I

For each protein make sure to provide the FASTA sequence that you used for the analysis and show me the result of your analysis that is a screenshot of the expanded tabs in PredictProtein software and a screenshot of what you see on MolView Use a different page to work on questions 1 4 or 5 8 2 Chain B PROTEIN BOVINE SEMINAL RIBONUCLEASE Accession 11BG B Provide the protein sequence 5 How many a helices and how many strands of three or more amino acids are predicted in this protein Secondary Structure RePROF Solvent Accessibility RePROF Topology TMSEG Disordered Region Meta Disorder Relative B Value PROFbval Protein Binding ProNA DNA Binding ProNA RNA Binding ProNA Disulfide Bond DISULFIND Conservation ConSeq 20 7 Secondary Structure RePROF Other Helix Strand Solvent Accessibility RePROF Exposed Buried Topology TMSEG Disordered Region Meta Disorder Disordered Region Relative B Value PROFbval 00 30 Low 31 70 Intermediate 71 99 High Protein Binding ProNA Protein Binding RI 00 33 Protein Binding RI 34 66 DNA Binding ProNA RNA Binding ProNA Disulfide Bond DISULFIND Disulfide Bond Conservation ConSeq Conservation Score 1 31 Low Conservation Score 4 6 I E 100 I 77 77

3 Using only the results obtained from this analysis i e do not have to go to wikipedia to read about it what is this protein predicted to bind to 4 Use MolView to explore this protein What can you say about the native structure of the protein Provide an image that substantiates your claim 7 points Secondary Structure RePROF Solvent Accessibility RePROF Topology TMSEG Disordered Region Meta Disorder Relative B Value PROFbval Protein Binding ProNA DNA Binding ProNA RNA Binding ProNA Disulfide Bond DISULFIND Conservation ConSeq Secondary Structure RePROF Other Helix Strand Solvent Accessibility RePROF Exposed Buried Topology TMSEG Disordered Region Meta Disorder Disordered Region Relative B Value PROFbval 00 30 Low 71 99 High 31 70 Intermediate Protein Binding ProNA Protein Binding RI 00 33 Protein Binding RI 34 66 DNA Binding ProNA RNA Binding ProNA IIIIII 1 I WILH Disulfide Bond DISULFIND Conservation ConSeq 100 Conservation Score 1 3 Low Conservation Score 4 6 Intermediate 200 I 1 I

4 Use MolView to explore this protein What can you say about the native structure of the protein Provide an image that substantiates your claim 7 points

Pattern baldness is an X linked recessive trait Can a man with pattern baldness have a daughter with pattern baldness Select the correct Punnett Square No there is never a possibility of a daughter having an X linked recessive disorder Yes O O xb yb Yes Xb yb Yes xb Y Yes xb Y XB XB Xb XB Yb XB XB Xb XB yb XB XB Xb XBY XB XB Xb XB Y Xb Xb xb xb yb XB XB Xb XB yb Xb Xb xb xb Y XB XB Xb XB Y

1 What role did yellow journalism play in the Spanish American War 2 Explain the significance of Alfred T Mahan s words on American imperialism

Freckles are dominant to having no freckles The trait is autosomal and follows the rules for complete dominance Select the two Punnett Square crosses that are possible for a father who has freckles and a mother who has no freckles Select 2 correct answer s 0 F f F LL F LL F f Ff T ff FF ff F FF Ff f Ff Ff F FF Ff Ff FfFf FFff FF FFFF FFff f F FF Ff f Ff Ff f Ff ff ff FFff ffff ff FFff ffff f

2 Pretend you are one of the people mentioned in question 1 Think about and describe how your life will change as a result of the General Act 3 King Leopold II of Belgium referred to Africa as that magnificent African cake What do you think he meant

What is your opinion on social media This could be social media in general or one particular platform TikTok Instagram Snapchat Facebook

Starch is a polymer of a D glucose a L glucose OB D glucose OB L glucose

OB H H I OD H H I OC N C C H OA H HICIR N C C H HICIR H H N C C HICIR HICIR O 0 0 O N C C O O OH

Which of these lipids has the highest Tm A B C D A BUD A B C D OHHHHHHHHHHH H II II H O C C C C C C C C C C C C H TTTTTTTTTTT HHHHHHHHHHH OHHHHHHHHHHHHH IIIIIIIIIIII H 0 C C C C C C C C C C C C C C H IIIIIIIIIIIII HHHHHHHHHHHHH OHHHHHHHHHHHHHHHHH HIIIIIIIIIIIIIIIII H 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 0 H IIIIIIIIIIIIIIIII HHHHHHHHHHHHHHHHH OHHHHHHH IIIIIIIH HHHHHHHH IIIIIIII H 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 0 H IIIIIIIIIIIII HHHHHHHHHHHHHHHHH

Which levels of structure are affected by urea Select all that apply Answer any level that is at least partially but directly affected by urea even if elements of that structure may remain Primary Secondary Tertiary 00 Quaternary

O Macmillan Leaming To paraphrase the article a variety of antibodies on the order of one hundred million different types circulale bloodstream searching for foreign invaders to attack Once discovered the antibody binds the invader with its Bexible arms containing the Fab region Thin flexible chains connect these flexible arms to the antibody base called the Fe region This base determines which class the antibody belongs to as same antibodies have four or ten binding sites due to their structural formation The figure shows the first immunoglobulin image derived from PDB ID 11GT in the article Label the light and heavy chains on the structure How many specific antigen binding sites are there on the immunoglobulin molecule depicted number of specific antigen binding sites one week Arewer Bank light chains instantly one month When a virus enters your lungs how long does it take for you to produce one or more antibodies that bind to it barvy chain

Which of these lipids has the lowest Tm A B C D A B C D OH OH OH OH 20 C 18 C 16 C 14 C

In winter many organisms adapt to the cold temperatures by increasing the fluidity of their membranes Which of the following would accomplish this Decreasing the effective membrane Tm Decreasing the length of its fatty acid chains Decreasing the saturation of its fatty acid chains All of the above

Which of the following molecules can we say is most amphipathic O Phospholipids Triglycerides Cholesterol Fatty acids

Under appropriate conditions hemoglobin dissociates into its four subunits The isolated a subunit binds oxygen but the O saturation curve is hyperbolic rather than sigmoid In addition the binding of oxygen to the isolated a subunit is not affected by the presence of H CO or BPG What do these observations indicate about the source of the cooperativity in hemoglobin Individual subunits are capable of binding O cooperatively BPG regulates the cooperative behavior of hemoglobin Cooperativity arises from the bicarbonate buffer system The cooperative behavior of hemoglobin arises from subunit interactions

The plot shows an oxygen binding curve for human hemoglobin Y fractional saturation 1 0 0 5 2 1 4 6 po kPa 00 8 10 For the each condition indicate whether the stated physiological change would shift the curve to the left produce no change o shift the curve to the right An increase in the concentration of CO would An increase in the proton concentration decrease in pH would An increase in the concentration of 2 3 bisphosphoglycerate BPG would

Learning O Macmil You are a technician in a biochemistry lab running receptor binding experiments The target membrane bound receptor has been partially purified from mouse rat and human cell lines Using the same radioactive ligand in a saturation binding assay for each species receptor you generate the binding data in the table The dependent variable Y is the fraction of binding sites occupied by the ligand Ligand concentration nM 0 20 0 50 1 0 4 0 10 20 50 human receptor K rat human Y for mouse receptor 0 048 0 11 mouse 0 20 0 50 0 71 0 83 0 93 Y for rat Y for human receptor receptor Determine the K for the human receptor in this binding experiment Which receptor binds most tightly to this ligand 0 29 0 50 0 67 0 89 0 95 0 97 0 99 0 17 0 33 0 50 0 80 0 91 0 95 0 98 nM

Imagine you are on a contestant on a new biochemistry game show Your first test is to identify an unknown polysaccharide You begin by treating it with specific enzymes that are capable of breaking down certain types of glycosidic linkages You find that only an enzyme that breaks beta 1 4 linkages is capable of degrading the polysaccharide into monomers You do chemical analysis and find that the monomers are glucose What type of polysaccharide could this be Select all that apply starch cellulose glycogen None of these