Principles of Inheritance & Variation (Genetics) Questions and Answers
Biology
Principles of Inheritance & Variation (Genetics)In rock roses, flowers come in three shades of pink: coral, salmon, and burgundy. If a pure-breeding coral plant is crossed with a pure-breeding burgundy plant, all the offspring are salmon. Which of the following is probably true?
The heterozygote plants' flower color is burgundy.
Plants with salmon flowers have an advantage over coral and burgundy flowers.
These roses have three alleles controlling flower color.
The heterozygote plants' flower color is salmon.
The heterozygote plants' flower color is coral.
Biology
Principles of Inheritance & Variation (Genetics)When considering recessive alleles, these alleles are most commonly explained by:
a sequence change that makes a poisonous protein
a sequence change that causes a gain-of-function mutation
a sequence change that causes a loss-of-function mutation
a sequence change that expresses a protein with redundant function
Biology
Principles of Inheritance & Variation (Genetics)You are given two true-breeding groups of gerbils. The gerbils in the first group have black fur and curly tails; the gerbils in the second group have yellow fur and straight tails. When you produce an F1 generation, you see only gerbils with black fur and curly tails. When you produce an F2 generation, you see that 75% of the gerbils have black fur and 25% have yellow fur. You also see that 25% of the gerbils have straight tails and 75% have curly tails. If the single alleles responsible for coat color and tall appearance sort independently, how many of the black gerbils in this generation are expected to have straight tails?
25%
0%
75%
100%
Biology
Principles of Inheritance & Variation (Genetics)A recessive disease shows incomplete penetrance such that only 50% of individuals that are
homozygous recessive actually express the disease. If two heterozygous individuals have two
children, what is the probability that neither of the children have the disease?
A) 1/8
B) 27/64
C) 1/16
D) 49/64
Biology
Principles of Inheritance & Variation (Genetics)A gardener is crossing flowers displaying complete dominance for flower color. The purple (P) trait is dominant and the white trait is recessive (p) The gardener performs hybridization with two pure-bred individuals (Purple x White) to create F1 offspring What is the genotype of the F1 flowers?
Purple
PP
White
Pp
pp
Biology
Principles of Inheritance & Variation (Genetics)In the garden pea, yellow cotyledon color is dominant to green, and inflated pod shape is dominant to the constricted form. A homozygous dominant yellow inflated plant is crossed with a homozygous recessive green constricted plant. All of the F1 generation were yellow and inflated. The following are the results for the F2 generation in which 994 peas were counted.
193 green, inflated
184 yellow constricted
556 yellow, inflated
61 green, constricted
Do the results agree with classical Mendelian genetics? Make a hypothesis, and support your answer using Chi-square analysis.
Biology
Principles of Inheritance & Variation (Genetics)Huntington's disease arises from a single mutation in a gene. The Huntington's mutation is dominant (A). Sickle Cell Anemia arises from a single mutation in a gene as well. The Sickle Cell mutation is recessive (a).
If an individual has the heterozygous genotype (Aa), which of the following diseases would be present or "show up"?
Huntington's
Sickle Cell
Biology
Principles of Inheritance & Variation (Genetics)Sickle Cell Anemia arises from a single mutation in a gene. The Sickle Cell mutation is recessive (a).
Which of the following individual genotypes would have Sickle Cell Anemia?
aa
ABA
AA
Aa
Biology
Principles of Inheritance & Variation (Genetics)In tracking the white gene in Drosophila that was discussed in class, a true-breeding
white-eyed female fly is crossed to a red-eyed male fly. If a single nondisjunction event of the sex-chromosomes occurs in meiosis I in this red-eyed male fly, what is the genotype and phenotype of an exceptional progeny (one with an abnormal number of sex-chromosomes) that could result from this nondisjunction event? (O = no sex chromosome)
A) X^w/X^w/Y white-eyed female
B) X^w/X^w+/Y red-eyed female
C) X^w/O white-eyed female
D) X^w+/O red-eyed male
E) X^w+/Y red-eyed male
Biology
Principles of Inheritance & Variation (Genetics)Certain genetic diseases are associated with particular populations because among major factors in establishing high frequencies of particular alleles in specific populations include
inbreeding in small populations
the preference for consanguineous matings in many societies
the founder principle operating in small migrant populations
all of the above
Biology
Principles of Inheritance & Variation (Genetics)Cross a homozygous tasting and unattached earlobe parent with a homozygous non-tasting
attached earlobe parent. What is/are the possible genotype(s) of the offspring?
TTFF and ttff
TtFf and TTFF
TtFf, TTFF and ttff
TtFf and TtFF
TtFf
Biology
Principles of Inheritance & Variation (Genetics)In certain wild animals with normally black fur there occurs a very strange kind of coloring that is
known as agouti. Each hair in the fur is black, but just below the tip, the hair has a band of yellow.
With thousands of these yellow bands the fur of the animal does not look black. It has a mousy
brown color. A strain of pure agouti mice was crossed with pure black mice. The result was ALL
agouti mice. When the P2 offspring agouti mice were crossed with each other, the resulting
offspring showed three times as many agouti mice as black mice. Which trait is dominant?
Black
Agouti
white
cannot be determined
Biology
Principles of Inheritance & Variation (Genetics)Which of the following are true about DNA and RNA (select all that apply)?
DNA is a much larger molecule than RNA
DNA is double stranded while RNA is single stranded
DNA contains the nucleotides ATCG while RNA contains the nucleotides AUCG
DNA contains the sugar ribose while RNA contains the sugar deoxyribose
Biology
Principles of Inheritance & Variation (Genetics)Indicate whether the genotype listed is heterozygous, homozygous recessive or homozygous
dominant
homozygous recessive
heterozygous
homozygous dominant
Biology
Principles of Inheritance & Variation (Genetics)Color blindness is recessive, x-linked trait. In marriages between a man who is colorblind and a woman who is a carrier what percentage of the children can be expected to be sons who are not color blind? What percentage of the children can be expected to be daughters who are carriers? What percentage of the children can be expected to be daughters who are not carriers at all?
Biology
Principles of Inheritance & Variation (Genetics)A pea plant is heterozygous for both seed shape and seed color. S is the allele for the dominant, spherical shape characteristic; s is the allele for the recessive, dented shape characteristic. Y is the allele for the dominant, yellow color characteristic; y is the allele for the recessive, green color characteristic.
What genetic cross would give a phenotypic ratio of 9:3:3:1?
Biology
Principles of Inheritance & Variation (Genetics)Brown eyes are dominant to blue eyes. What is the phenotype for a person with the following genotypes?
BB
Bb
bb
Biology
Principles of Inheritance & Variation (Genetics)What differs between two alleles of the same gene?
The cell they're in. One might be in a liver cell and the other in a blood cell.
The chromosome they're on. One might be on Chromosome 12 and the other on chromosome 3.
Their location. One allele might be at the end of chromosome while the other allele is in the middle of another chromosome.
Their base sequence. One allele might have the base sequence AGGTCTGA while the other has the base sequence GGTCTGT.
Biology
Principles of Inheritance & Variation (Genetics)Which of the following is a result of T.H. Morgan and Lynch's (1912) study on linkage?
phenotypic combinations in the F2 generation were not found in equal ratios
no new phenotypic combinations appeared in the F2 generation
inheritance in the F2 generation results in a 1:1:1:1 phenotypic ratio
only recombinant phenotypes were present in the F2 generation
Biology
Principles of Inheritance & Variation (Genetics)If genes are "sex-linked," then they are
expressed only in women or only in men
typically on the X chromosome
only on the Y chromosome
located next to one another
Biology
Principles of Inheritance & Variation (Genetics)Assuming incomplete dominance, if a homozygous red-flowered plant (RR) is crossed with a homozygous white-flowered (rr) plant, what will be the color of the offspring?
White
red and white
Red
pink
Biology
Principles of Inheritance & Variation (Genetics)Which discovery did Gregor Mendel make?
Traits are inherited independently of each other.
Traits are inherited as a tetrad.
Traits are inherited as homologous pairs.
Traits are inherited as a set, from one parent.
Biology
Principles of Inheritance & Variation (Genetics)UV radiation is an ionization radiation that is useful for disinfecting surfaces
True
False
Biology
Principles of Inheritance & Variation (Genetics)Cross a homozygous green plant with a heterozygous green plant.
Biology
Principles of Inheritance & Variation (Genetics)Instructions: Students will need to show all work including writing out the crosses and the resulting gametes as well as Punnett squares. The final responses need to be marked with a box or circle around them.
1a) Mendel determined that yellow seeds is dominant to green seeds in peas. Cross a pea plant which is homozygous for yellow seeds with one which has green seeds. (Use capital letters for the dominant trait and the same letter in lower case for the recessive trait). What is the expected genotypic ratio of the offspring (F1)? What is the expected phenotypic ratio?
1b) If the F1 plants in the previous problem were allowed to self-fertilize, what is the expected genotypic ratio in the F2? What is the expected phenotypic ratio? Show the problem.
Biology
Principles of Inheritance & Variation (Genetics)Snapdragon flower color is an example of incomplete dominance. A) Cross a white-flowering plant with a red-flowering plant. What are the expected genotypic and phenotypic ratios in the F1? B) Now cross two pink snapdragons. Give the expected genotypic and phenotypic ratios in the offspring.
Biology
Principles of Inheritance & Variation (Genetics)In human blood types Type A and B are co-dominant while Type O is recessive to both A and B. If a Type A individual marries a Type O individual, can they have a Type O child? Why/why not? Can they have a Type AB child? Why/Why not?
Biology
Principles of Inheritance & Variation (Genetics)Hemophilia is a recessive, sex-linked disease. a) A male with no history of hemophilia marries a woman whose father was a hemophiliac. Of their sons, what proportion would be expected to be hemophiliacs? What proportion of the daughters? What proportion of their total children would be expected to be carriers of the disease (having the gene, but not exhibiting the disease)? b) What if the male parent was a hemophiliac and the female parent had no history
of the disease? (answer the same information as part a)
Biology
Principles of Inheritance & Variation (Genetics)In summer squash, yellow fruit color dominates over white. A white-fruited plant is crossed with a yellow-fruited one and produced 51 white and 49 yellow fruited plants.
Biology
Principles of Inheritance & Variation (Genetics)In alligators, rounded snout is dominant to a pointed snout. Cross a homozygous rounded snout alligator with a pointed snout alligator. What are the expected genotypic and phenotypic rations in the F2?
Biology
Principles of Inheritance & Variation (Genetics)In humans, color-blindness is a recessive, sex-linked disease. A male who is color-blind marries a woman with normal vision but whose father was color-blind. OF THEIR SONS, how many can be expected to be color-blind? How many of their daughters can be expected to be color-blind? Are any of their children carriers of the disease (having the allele, but not expressing it)? How many? Are these carriers male or female?
Biology
Principles of Inheritance & Variation (Genetics)In humans, blood Rh factor is an example of complete dominance (alleles for "positive" Rh factor completely dominate the "negative" allele). Blood type is an example of co-dominance. A person who is type AB and is heterozygous for Rh factor marries an individual who is O-. What are the chances that they will have a child with Type A+ blood? What are the chances that they will have a child with Type B- blood? Can they have a child with type O+ blood? Why or why not? (Hint: handle this as a di-hybrid cross).
Biology
Principles of Inheritance & Variation (Genetics)3a) In tomatoes the skin may be smooth or hairy. Crosses between a true- breeding smooth-skinned tomato and a true-breeding hairy tomato produce all smooth fruit. (HINT: this should tell you which trait is dominant.) Show the Punnet Square for the problem and give the expected genotypic and phenotypic ratios in the offspring.
3b) Cross one of the F1 individuals from the previous problem with a homozygous smooth-skinned plant. Now cross the same F1 individual with a homozygous hairy plant. What are the expected genotypic and phenotypic ratios in the offspring?
Biology
Principles of Inheritance & Variation (Genetics)In Pine trees, cones may be small or large. A true-breeding, small-coned plant is crossed with a true breeding large-coned plant. All offspring are large-coned. Which trait is dominant and which is recessive? How do you know?
Biology
Principles of Inheritance & Variation (Genetics)A female who is color blind marries a male with no history of the condition. Show the problem. Of their children, what proportion would be expected to be color blind? Are these sons or daughters or both? Are any children carriers (having the gene, but not expressing the condition)? Are these sons or daughters or both?
Biology
Principles of Inheritance & Variation (Genetics)Cross two pink-flowering Snapdragons. What are the expected genotypic and phenotypic ratios in their offspring?
Biology
Principles of Inheritance & Variation (Genetics)A female with type A- blood marries a male with type AB+ blood. The female is heterozygous for blood type. The male is heterozygous for rh factor. Show the problem. What are the expected genotypic and phenotypic ratios in their offspring?
Biology
Principles of Inheritance & Variation (Genetics)In sea horses long tail is dominant to short, and thick scales is dominant to thin. Cross two seahorses that are heterozygous for both traits. What are the expected genotypic and phenotypic ratios in the F1?
Biology
Principles of Inheritance & Variation (Genetics)In Humans, long eyelashes is dominant to short. A female with long eyelashes marries a man who also has long eyelashes. They have a daughter with short eyelashes. How is this possible? Show the problem.
Biology
Principles of Inheritance & Variation (Genetics)In Coleus plants, deep leaf margins are dominant over shallow leaf margins. Red leaves is dominant over green. If an individual that was heterozygous for both traits was crossed with a shallow-margined, green-leafed plant, what proportion of the F1 would have deep leaf margins AND red leaves? Show the problem.
Biology
Principles of Inheritance & Variation (Genetics)A large-coned plant from the problem above is crossed with a small-coned plant. They produce 735 offspring. 351 offspring were small-coned, while 384 were large-coned. What are the genotypes of the parents? How do you know? Show the punnet square.
Biology
Principles of Inheritance & Variation (Genetics)What are the two main sources of genetic variation in organisms?
mutation and genetic drift
gene flow and genetic drift
natural selection and mutation
mutation and sexual reproduction
Biology
Principles of Inheritance & Variation (Genetics)In a group of cucumber plants, some individuals have bumpy fruit and others have smooth fruit. In this group, the gene for the fruit texture trait has two alleles. The allele F is for bumpy fruit, and the allele f is for smooth fruit.
A certain cucumber plant from this group has bumpy fruit. This plant has one allele for bumpy fruit and one allele for smooth fruit.
Based on this information, what is this cucumber plant's genotype for the fruit texture gene?
Biology
Principles of Inheritance & Variation (Genetics)Inheritance and Expression of Traits:Question 5
Which molecule stores the instructions for various traits in an organism?
Select one:
Carbohydrate.
Lipid.
Protein.
Deoxyribonucleic acid.
Biology
Principles of Inheritance & Variation (Genetics)A deletion mutation causes three consecutive nucleotides to be
removed from the DNA code.
Which options describe the possible effects of this mutation?
se all that apply:
One amino acid may not be present. The rest of the amino acids would be
in the protein in the correct order.
The codons up to the affected region may be read incorrectly.
The codons from the affected region onward may be read incorrectly.
Three amino acids may not be present. The rest of the amino acids would
be in the protein in the correct order.
Biology
Principles of Inheritance & Variation (Genetics)Genetic Diversity and Population Survival:Question 9
Which of these results from making the sperm and egg cells
needed for sexual reproduction?
An introduction of a new gene into the organism.
The loss of nucleotides from the DNA.
An offspring that has the exact same genetic makeup as
its parents.
A large reshuffling of genetic information.
Biology
Principles of Inheritance & Variation (Genetics)Synthesis of an inducible enzyme is started by the
O inducer inactivating repressor
O corepressor activating repressor and binding to operator
O corepressor binding to the operator
Biology
Principles of Inheritance & Variation (Genetics)Which of the
following is the
study of heredity
and how genetic
information is
transferred from
parents to their
offspring?
A. Genetics
B. Biology
C. Geneology
Biology
Principles of Inheritance & Variation (Genetics)In dogs, the allele for straight hair (H) is dominant to the allele for curly hair (h). A straight-haired dog is crossed with another straight-haired dog. They produce only two puppies, one with straight hair and one with curly hair. Based on these results, what are the genotypes of the two parent dogs?
A. One is heterozygous and the other is homozygous dominant
B. One is homozygous dominant and the other is homozygous recessive
C. One is heterozygous and the other is homozygous recessive
D. Both are heterozygous
Biology
Principles of Inheritance & Variation (Genetics)In Drosophila melanogaster, the black body (b*) is recessive to the gray body (b*), purple eyes (pr) are recessive to red eyes (pr*), and vestigial wings (vg) are recessive to normal wings (vg*). The loci encoding these traits are linked, with the map distances shown in the image.
The interference among these genes is 0.5. A fly with a black body, purple eyes, and vestigial wings is crossed with a fly homozygous for a gray body, red eyes, and normal wings. The female progeny are then crossed with males that have a black
body, purple eyes, and vestigial wings.
If a total of 1000 progeny are examined, determine the expected number of offspring that result from each crossover event.
double crossover:
single crossover between b and pr:
single crossover between vg and pr: