Suppose Alia recently learned that she inherited a mutant BRCA1 allele from her mother, who had breast cancer. BRCAI is a tumor

Question

Suppose Alia recently learned that she inherited a mutant BRCA1 allele from her mother, who had breast cancer. BRCAI is a tumor suppressor gene that is related to breast cancer.

Why would Alia be at higher risk for getting breast cancer at an earlier age than her sister, Francine, who inherited a normal BRCA1 allele from their mother?

If an individual has even one mutation in a tumor suppressor gene, cancer will not be suppressed. 
Someone with one mutant allele in a tumor suppressor gene only requires a mutation in the one remaining normal allele for tumors to form. 
An individual who inherited two functional alleles of a tumor suppressor gene is less likely to eat highly carcinogenic foods. 
One mutant allele of a tumor suppressor gene increases the likelihood that the wild-type allele will also mutate

Kunduz · Accepted Answer

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