13 Tacrolimus FK 506 is a drug that inhibits an enzyme called calcineurin Calcineurin is a protein phosphatase This is an enzyme

Question

13 Tacrolimus FK 506 is a drug that inhibits an enzyme called calcineurin Calcineurin is a protein phosphatase This is an enzyme that dephosphorylates removes phosphate groups from proteins When added to cells tacrolimus can inhibit the dephosphorylation of a protein called NFAT but it cannot prevent the dephosphorylation of a protein called CDK1 What is the most likely explanation for this finding Multiple Choice Tacrolimus is a competitive inhibitor of calcineurin for NFAT and CDK11 O Calcineurin requires an additional cofactor to dephosphorylate NFAT O Tacrolimus changes the optimum pH for calcineurin NFAT is a substrate of calcineurin but CDK1 is not

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