Amyloidosis is caused by an abnormal deposition and

Last updated: 7/8/2022

Amyloidosis is caused by an abnormal deposition and accumulation of protein aggregates in tissues. How do proteins adopt and maintain a stable folded structure? What features of the protein amino acid sequence determine the stability of the folded structure? How does disruption of that structure lead to protein deposition diseases such as amyloidosis, Alzheimer's disease, and Parkinson's disease?