In people with xeroderma pigmentosa thymine dimers are

Last updated: 4/15/2023

In people with xeroderma pigmentosa thymine dimers are formed which distort the structure of the DNA double helix causing problems during DNA replication and increasing the risk of skin cancer It is due to a defect in the enzymes which would normally repair the results of UV radiation induced mutations transversion substitution nucleotide excision repair mismatch repair transition substitution