p53 is a tumor suppressor gene mutations in p53 are seen in more than 50 of all cancers Which of the following mutations in p53

Question

p53 is a tumor suppressor gene mutations in p53 are seen in more than 50 of all cancers Which of the following mutations in p53 would likely increase cell division rate predisposing an individual to cancer Sort each mutation into the correct bin to identify it as more likely to be cancer causing or more likely to be non cancer causing A translocation that puts the p53 gene near an active repressor region of DNA such that p53 is not transcribed Duplication of the p53 gene Deletion of one copy of the p53 gene Methylation of CpG islands near the p53 promoter region A nonsense mutation close to the start codon of p53 such that no functional p53 protein is made A missense mutation in the p53 gene that increases the activity of the p53 protein Cancer causing Non cancer causing

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