Sar1 GTPase plays an important role in COPII coat formation

Last updated: 5/17/2023

Sar1 GTPase plays an important role in COPII coat formation Scientists generated a Sar1 GTPase mutant in which the GTPase activity is lost How this mutant would affect the COPII mediated transport No effect would be observed COPII coated vesicles can t form at all COPII coated vesicles can form but the coat can t be disassembled and thus the vesicles can t fuse with the target membrane COPII coated vesicles can form normally but the coat can t be disassembled However the coated vesicles can still dock and fused with the target membrane