Sickle Cell Anemia (SCA) is a genetic anomaly that causes

Last updated: 7/8/2022

Sickle Cell Anemia (SCA) is a genetic anomaly that causes blood vessels to sickle when under oxygen stress. These sickled cells can get stuck in the capillaries of the body, cause pain, the loss of sight, the loss of limbs and even death. The protein hemoglobin B (HBB) is affected in this anomaly. Here is the normal DNA for a section of HBB GTG CAC CTC AGT CCA GAG GAG Mutated DNA: GTG CAC CTC AGT CCA GTG GAG a. What type of mutation caused the HBB gene to sickle? Please put an asterisk above the mutated DNA where the mutation occurred b. What are three symptoms of Sickle Cell Anemia? c. What did the mutation do to the shape of HBB?