What does it mean to say that extension by DNA polymerase

Last updated: 7/23/2022

What does it mean to say that extension by DNA polymerase III proceeds 5'-3'? The 5' end of a DNA polymerase molecule attaches to the 3' end of primase. DNA polymerase adds nucleotides to a growing strand, moving in the 5'-3' direction. DNA polymerase seals nicks as it moves along a DNA strand toward the 3' end. DNA polymerase can only synthesize DNA at the 5' end of an existing strand of DNA.