Alzheimer's disease is thought to be caused by a genetic

Last updated: 7/26/2022

Alzheimer's disease is thought to be caused by a genetic mutation that causes abnormal expression of the amyloid precursor protein (APP). Patients with Alzheimer's disease have abnormally high expression of APP, although the amino acid sequence of the protein itself is not always mutated. Given this, which of the following best describes the location of a genetic mutation that could result in the overexpression of APP in Alzheimer's disease patients? The promoter sequence The transcriptional stop site An intron sequence The region of transcribed mRNA The stop codon