Question:
Gleevec is a chemotherapy drug used to treat cancer. What is
Last updated: 7/8/2022
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Gleevec is a chemotherapy drug used to treat cancer. What is the mechanism by which Gleevec blocks Abl kinase enzyme action? Gleevec reduces the ATP level in the body and starves the Abl enzyme Gleevec purifies cancer cells and returns them to a normal functioning state Binding of Gleevec to the active site locks Abl in an inactive conformation Binding of Gleevec to the active site mutates threonine 315 to methionine Gleevec is a protease that cleaves the Abl protein at the regulatory spine