group 47 360 group Allele A 3 109 Allele C 2 640 46 891 O SNP 3 risk allele is A O SNP 1 risk allele is C O SNP 3 risk allele is

Question

group 47 360 group Allele A 3 109 Allele C 2 640 46 891 O SNP 3 risk allele is A O SNP 1 risk allele is C O SNP 3 risk allele is G Results are shown above for 3 biallelic SNPs on the same chromosome used in a GWAS examining SNP trait correlations for a complex human disease trait Table entries show the number of people with the indicated SNP allele that have the disease disease group or don t have the disease control group Which SNP would have the highest log10 p value score in a Manhattan plot summarizing results of this GWAS and which is the SNP risk allele O SNP 2 risk allele is T Allele C Allele T O SNP 2 risk allele is C O SNP 1 risk allele is A group group 25 350 24 133 24 650 25 867 group group Allele G 1 420 1 509 Allele A 48 580 48 491

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