Learning Goal: In the presence of a strong acid, such as

Last updated: 7/31/2022

Learning Goal: In the presence of a strong acid, such as HCl, an amide reacts with water to produce a carboxylic acid and an ammonium or amine salt. In the presence of a strong base, like NaOH, the amide reacts to produce ammonia or an amine, and a carboxylic acid salt. Acetaminophen is an analgesic marketed under the brand name Tylenol, among others. (Figure 1) Draw the amine that results from the base hydrolysis of acetaminophen.