Mutations in the adenomatous polyposis coli APC gene

Last updated: 8/16/2023

Mutations in the adenomatous polyposis coli APC gene increase the risk of developing colorectal cancer The partial DNA sequences shown are on the coding strand of the APC gene from Jamal who does not have cancer and Jana who was diagnosed with colorectal cancer The sequences are in frame with the start codon not shown What type of mutation does Jana likely have Consult a codon table to answer this question Jamal 5 GAG GCG GGT TCA CGA GAG 3 Jana 5 GAG GCG GGT TGA CGA GAG O Frameshift O Missense Silent Nonsense 3