Second messenger cyclic AMP CAMP is synthesized from ATP by the activity of the enzyme adenylyl cyclase Cyclic AMP n turn

Question

Second messenger cyclic AMP CAMP is synthesized from ATP by the activity of the enzyme adenylyl cyclase Cyclic AMP n turn activates protein kinase A PKA also called CAMP dependent protein kinase which is responsible for most of the effects of cAMP within the cell Determine the correct steps in the activation of PKA and then place them in the correct order starting after the adenylyl yclase reaction Answer Bank The regulatory subunits dissociate from the catalytic subunits Two CAMP molecules bind to each PKA regulatory subunit Cytosolic CAMP concentration increases Cytosolic CAMP concentration decreases Each regulatory subunit is activated as the two CAMP molecules release The free catalytic subunits inct with proteins to phosphorylate Ser or

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