Question:

Step one of glycolysis is irreversible in muscle cells,

Last updated: 8/2/2022

Step one of glycolysis is irreversible in muscle cells,

Step one of glycolysis is irreversible in muscle cells, meaning that glucose-6-phosphate is not easily converted back to glucose. Why would this beneficial to muscle cells? (optional) Glucose-6-phosphate is an allosteric inhibitor of hexokinase, the enzyme that catalyzes reaction 1 of glycolysis. Review the section in your text about enzyme inhibitors. a. How does an allosteric inhibitor work? b. Why would this enzyme be a good target for regulation by inhibition?