What feature of DNA replication did Fred Sanger cleverly take advantage of when he invented dideoxy DNA sequencing using ddNTPs

Question

What feature of DNA replication did Fred Sanger cleverly take advantage of when he invented dideoxy DNA sequencing using ddNTPs Heat denatures hydrogen bonds between As and Ts at a lower temperature than Cs and Gs Wobble rules allow occasional mispairing of bases RNA nucleotides are degraded faster because they have a 2 OH Ligase creates a phosphodiester bond ODNA polymerase can only add new nucleotides to a 3 OH

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