David Pribnow studied the base sequences of promoters in

Last updated: 7/9/2022

David Pribnow studied the base sequences of promoters in bacteria and bacterial viruses. He found two conserved regions in these promoters (the -10 box and the -35 box). These two regions of the promoter . signal the initiation site bind the sigma subunit that is associated with RNA polymerase attach the correct nucleotide triphosphate to the template DNA strand separate the two DNA strands