Question:
mistry What is the right option and why The figure below
Last updated: 5/11/2023
mistry What is the right option and why The figure below shows a cartoon of the reaction of a lactam antibiotic in the active site of transpeptidase R OH SER R The mechanism of reaction is SN2 IZ Which ONE of the following statements about the reaction is INCORRECT HN SER The B lactam has reactivity similar to an ester The product ester is protected from bulk water and enzymes so is not easily hydrolysed The driving force for the reaction comes from release of ring strain in the B lactam The carboxylate group could form an ion pair with amino acid residues of the protein S