Pre orRNA processed into mature crRNA Phage infects the

Last updated: 4/23/2023

Pre orRNA processed into mature crRNA Phage infects the bacterial cell with its DNA Phage DNA incorporated as a new spacer into CRISPR crRNA Cas machinery cuts complementary target DNA of invading phage Mature crRNA forms complex with Cas nuclease Transcription of CRISPR locus yielding pre crRNA crRNA BIOGENESIS SPACER ACQUISITION INTERFERENCE Group 1 Group 1 10 O Group 1 Group 1 Group 1 Group 1 1 1 Group 2 Group 2 Group 2