The cholera toxin produces massive diarrhea and dehydration and possible death if not treated The toxin ultimately affects a

Question

The cholera toxin produces massive diarrhea and dehydration and possible death if not treated The toxin ultimately affects a chloride channel which is controlled by ATP Activation of the channel results in the efflux of chloride out of the cells of the intestine Sodium follows chloride and water follows producing the diarrhea How is the chloride channel activated Adenosine binds to the chloride channel causing the conformational change and the channel opens ADP binds to the chloride channel causing the conformational change of the channel and the channel opens The channel is dephosphorylated causing the conformational change and the channel opens ATP hydrolyzes producing ADP and Pi The inorganic phosphate causes a conformational change and the channel opens

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