What actually dictates the 5 3 direction of DNA replication

Last updated: 8/4/2023

What actually dictates the 5 3 direction of DNA replication O Okazaki fragments are not sterically hindered by 2 OH found in ribonucleotides making the 5 to 3 synthesis possible on both strands O What actually dictates the 5 3 direction of DNA replication The direction of polymerization is determined by primase not the nucleotide structure The triphosphate on 5 OH undergoes a nucleophilic attack by Mg2 in DNA polymerase The nucleophilic attack of the 3 hydroxyl group on the 5 phosphate group allows energy to be obtained from hydrolysis of pyrophosphate on the 5 end