Principles of Inheritance & Variation (Genetics) Questions and Answers
Biology
Principles of Inheritance & Variation (Genetics)A scientist is trying to determine the relationship between clams, snails, and squid. When she generates a molecular clock, she is surprised to see that clams and squid are more closely related than clams and snails. Which did the molecular clock data show?
Clams and squid have been evolving separately for a longer time than clams and snails.
Clams and squid have been evolving separately for a shorter time than clams and snails.
Clams and snails have more in common genetically than clams and squid.
Clams and snails are more similar in related structures than clams and squids.
Biology
Principles of Inheritance & Variation (Genetics)A woman has a rare Mendelian abnormality of the eyelids called ptosis, which prevents her from opening her eyes completely. This condition is caused by a dominant allele, Z. The woman's father had ptosis, but her mother had normal eyelids. Her father's mother had normal eyelids but his dad had ptosis. (To help answer the questions below, draw out the pedigree and add any known alleles/genotypes)
a. What is the affected woman's genotype? Blank 1
b. What is genotype of the woman's father? Blank 2
c. What is the genotype of the woman's mother? Blank 3
d. What percentage of the woman's children will have ptosis if she marries a man with normal eyelids? Blank 4%
Blank 1
Blank 2
Blank 3
Blank 4
Biology
Principles of Inheritance & Variation (Genetics)The following statement are all false except for one
a. Meiosis create genetic diversity during prophase I (crossing over) and anaphase I (independant assortment of homologous
chromosomes)
b. Meiosis create genetic diversity during prophase II (crossing over) and anaphase II (independant assortment of homologous
chromosomes)
c. During Anaphase II chromosomes only have 2 chromatids
d. During Anaphase I chromosomes only have 1 chromatid
e. Meiosis only create diploid cells which will be used during fertilization
Biology
Principles of Inheritance & Variation (Genetics)Concordance refers to
percentage of monozygotic twin pairs in which both express the trait.
percentage of monozygotic twin pairs in which neither express the trait.
percentage of twin pairs in which both express a trait among pairs in which at least one twin
has the trait.
percentage of dizygotic twin pairs in which both express the trait.
Biology
Principles of Inheritance & Variation (Genetics)Heritability of a trait can change because
the heritability in a family changes with the number of children.
a person can consciously change her or his heritability.
the environment can change.
genes mutate.
Biology
Principles of Inheritance & Variation (Genetics)In cats and rabbits, an autosomal recessive mutation causes soft curly fur, called the rex coat. The dominant allele R causes straight fur.
An autosomal recessive mutation causes floppy ears, compared to the dominant straight ears (allele E).
If rabbits Rr ee and rr Ee were mated, what are the chances that they will produce bunnies with rex coat and floppy ears?
1/4
3/4
3/8
9/16
3/16
1/16
0
Biology
Principles of Inheritance & Variation (Genetics)Dimples is an autosomal dominant trait and no dimples is recessive.
Brown eye color is autosomal dominant, and and blue eye color is recessive.
If parents have Dd Bb and Dd bb genotypes, what is the chance that their child will have dimples and brown eyes?
1/8
1/4
3/8
5/16
9/16
3/16
0
1/16
Biology
Principles of Inheritance & Variation (Genetics)Being right-handed is an autosomal dominant trait over being left-handed. Hitchhiker
thumb is dominant over straight thumb trait.
Mary is right-handed and has a hitchhiker thumb.
Mary's mother is left-handed and has a hitchhiker thumb.
Mary's father is right-handed and has a straight thumb.
What is Mary's genotype?
rrHh
RrHh
Rrhh
RRHH
none of these
RRHH
Biology
Principles of Inheritance & Variation (Genetics)In dogs, short fur is recessive and long fur is dominant in an autosomal gene F. The classic moustache and eyebrows seen in schnauzers is an autosomal dominant trait (use gene R). Suppose a breeder has a dog who is heterozygous for both genes. What gametes does this dog produce?
fR
rr
ff
Fr
FFRR
FR
Ff Rr
fr
Biology
Principles of Inheritance & Variation (Genetics)A girl has dimples (dominant trait of autosomal gene D) and a cystic fibrosis (recessive disease from autosomal gene F). Which of these COULD be the genotype of her FATHER?
Hint: Draw a pedigree.
Mark all possible correct answers.
DD FF
Dd ff
dd ff
DD ff
Dd FF
dd Ff
Biology
Principles of Inheritance & Variation (Genetics)Black fur in mice is dominant to brown fur.
Short tails are dominant to long tails.
In a cross of Bb Tt x bb Tt, what fraction of the offspring will have black fur and short tails?
1/16
1/4
1/8
3/4
3/16
9/16
3/8
0
Biology
Principles of Inheritance & Variation (Genetics)Which are possible gametes of an organism that has Aa BB genotype? Genes A and B are autosomal.
Mark all correct answers.
AB
Ab
aB
aa
Aa
ab
bb
Bb
Biology
Principles of Inheritance & Variation (Genetics)In corn, red kernel color (R) is dominant to yellow (r) and smooth kernel texture (W) is dominant to wrinkled (w).
Corn heterozygous for kernel color and kernel texture are fertilized with corn that is yellow and wrinkled resulting in the following phenotypic offspring were observed:
red smooth; red wrinkled; yellow smooth; yellow wrinkled
A chi-square value of 25.52 was calculated from the data collected.
Answer the following questions:
a. What is expected from the cross described?
b. Why is this expected?
c. Based on the chi-square value given above, state whether observations matched expectations by referring to p-value and probability.
d. Do the data conform to Mendelian expectation?
d. If observations do not match expectations, discuss two possible reasons why
Biology
Principles of Inheritance & Variation (Genetics)The two interesting types of people who led researchers to discovery of the SRY gene were
XXX females and XYY males.
XY males and XX females.
XX males and XY females.
physicists and chemists.
Biology
Principles of Inheritance & Variation (Genetics)A human male inherits
an X chromosome from his mother and a Y chromosome from his father.
his father's Y chromosome and an X chromosome from either his father or mother.
an X chromosome from both parents.
both X and Y chromosomes from his father.
Biology
Principles of Inheritance & Variation (Genetics)Human females are the ________ sex.
homogametic
homozygous
hemizygous
heterozygous
Biology
Principles of Inheritance & Variation (Genetics)A type of rickets is a X-linked dominant trait. A female heterozygous for rickets and an
unaffected male are expecting a child. Determine the chances of this child inheriting
this type of rickets.
0%
100%
25%
50%
75%
Biology
Principles of Inheritance & Variation (Genetics)In humans, hemophilia is a X-linked recessive trait. If a female who is a carrier for
hemophilia marries a male with normal blood clotting have a child together.
Determine the possible genotypes of the child. Choose all that apply.
XHXH
xhxh
XHY
xHy
xhy
XHxh
Biology
Principles of Inheritance & Variation (Genetics)Human males are the
homozygous
heterozygous
homogametic
heterogametic
sex.
Biology
Principles of Inheritance & Variation (Genetics)In humans, Ichthyosis is a X-linked recessive disorder that causes persistently dry, thickened, 'fish scale' skin. Rosa and Stefan's newborn son Alan has been diagnosed with the disorder. Rosa and Stefan do not have the disorder and do not know of anyone in their family with the disease. Which parent passed the disease allele to Alan? If Rosa and Stefan have another child, what is the risk of that child suffering from hemophilia?
either Rosa or Stefan
Rosa only
Stefan only
cannot be determined
Biology
Principles of Inheritance & Variation (Genetics)Hemophilia is a sex-linked recessive condition that results in deficient blood clotting. The disease causes excessive bleeding which occurs spontaneously or upon slight injury. In dogs (as in humans) hemophilia is caused by a defect in a gene on the X chromosome.What will be the results of mating between a normal, non-carrier female dog and a male dog with hemophilia?
Half the femaleoffspring will have hemophilia and half will be carriers, all male offspringwill be normal.
All femaleoffspring will be normal and half the male offspring will have hemophilia.
All the femaleoffspring will be normal and all male offspring will be carriers.
All of theoffspring will be normal, but all females will be carriers.
Half the maleoffspring will be normal and half will have hemophilia; all females will becarriers.
Biology
Principles of Inheritance & Variation (Genetics)Which of these illustrates pleiotropy?
the genes for red eyes and hairy body in fruit flies are located on the same chromosome
human cystic fibrosis causes many symptoms from respiratory distress to digestive problems
mating between earless sheep and long eared sheep results in short eared offspring
wheat grains can range from white to red in color, a trait governed by multiple genes
Biology
Principles of Inheritance & Variation (Genetics)Trevor's biologic mother has type A blood and his biologic father has type B blood. Based on this information, it is correct to say that:
must have type A blood
must have type AB blood
must have type B blood
could have type O blood
Biology
Principles of Inheritance & Variation (Genetics)Your phenotype (hair color, eye color, blood type) is due to the specific __that your DNA codes the production of.
Select one:
a. RNA
b. Carbohydrates
c. Lipids
d. Proteins
Biology
Principles of Inheritance & Variation (Genetics)Allison has a newborn child that was the result of a sperm donor conceptions. She recently found out that the donor died from complications of neurofibromatosis type 1 (autosomal dominant). Her son tests negative for NF but she knows that the test has a 95% sensitivity and is not perfect.
Group of answer choices
1/33
1/65
1/21
Biology
Principles of Inheritance & Variation (Genetics)Cat fur color is determined by codominance. The allele for tan fur (TT) and the allele for black fur (BB) are codominant. The heterozygous condition (TB) results in a cat with tan and black spots, called a tabby cat. What would occur is a tan cat was crossed with a tabby cat? Draw the Punnett square and identify the genotypes and phenotypes of their offspring.
Biology
Principles of Inheritance & Variation (Genetics)Duchenne muscular dystrophy is a sex-linked recessive trait like other sex-linked
recessive traits such as Hemophilia or red/green color blindness that we talked
about in class. Complete the following Punnett squares and questions associated
with Duchenne muscular dystrophy.
2. Write the genotype of a woman who does not have Duchenne muscular
dystrophy.
3. Write the genotype of a woman with Duchenne muscular
dystrophy.
4. Write the genotype of a woman who is a carrier for Duchenne muscular
dystrophy.
5. Write the genotype of a man who has Duchenne muscular
dystrophy.
6. Write the genotype of a man who does not have Duchenne muscular
dystrophy.
Biology
Principles of Inheritance & Variation (Genetics)A long-eared mouse heterozygous for blue fur and homozygous recessive for the tailless condition is crossed to a blond mouse heterozygous for both a long tail and short ears. Using a branch diagram, determine the phenotypic ratio for the offspring. (dominant: Blue fur (B), tail present (T), short ears (E))
Biology
Principles of Inheritance & Variation (Genetics)Note: Gender in fruit flies is determined by the composition of the sex chromosomes, X & Y; females are XX and males are XY. In fruit flies, a new mutant phenotype called wingless (i.e. a fly with no wings) is found to be a recessive phenotype, while having wings is the wildtype (and dominant) phenotype. This trait is X- linked. A female that is homozygous with wings is mated to a male fly that is wingless. The F1 are intercrossed to produce an F2 generation. what is the genotype of female?
xt xt
xw xw
WW
++
xt xw
Biology
Principles of Inheritance & Variation (Genetics)While doing a pedigree analysis of a royal family from the ancient Mayan empire, you notice that a prince with a genetic disease married a person from outside the royal family without a history of the disease in her family. Of their six children, two have the disease and four were not affected. The prince's mother and father also had this disease. If this disease is controlled by a single gene, then the most likely explanation for its occurrence in the children would be that the disease is:
a spontaneous mutation.
dominant and is only seen in homozygous dominant individuals.
recessive and is only seen in homozygous recessive individuals such as the two affected children.
dominant and is seen in heterozygous or homozygous dominant individuals.
Biology
Principles of Inheritance & Variation (Genetics)You are attempting to determine the genotype of your C. bonita plant, which generates blush-colored blooms. A quick search tells you that pink blooms are the dominant phenotype; aqua blooms are the recessive phenotype for C. bonita blooms. Sadly, you don't have the capability to determine the genotype using DNA sequencing, but you can perform some mating experiments to help you determine the genotype of your blush- bloomed C. bonita plant.
a) If the plant was homozygous dominant, which type of bloom color allele - blush, aqua, or either - would you expect to find in the gametes of your C. bonita plant?
b) Using letters, define some alleles for bloom color in C. bonita.
c) Now that we've got all that settled, you've decided to run a testcross to help you determine the genotype of your blush-bloomed; this means you'll mate your blush-bloomed plant with an aqua plant. Using all of the information you have and using the letters you've defined in part b, what would be the genotype of that aqua plant?
d) You've completed your testcross and have some offspring - YAY! All of the offspring have blush- colored blooms. So, using those letters you've defined in part b, tell me the genotype of your parent blush-bloomed plant.
Biology
Principles of Inheritance & Variation (Genetics)If you cross Pure agouti x pure black, what is/are the offspring phenotype(s)?
all black
50% agouti, 50% black
75% agouti, 25% black
all agouti
Biology
Principles of Inheritance & Variation (Genetics)An X-linked recessive gene c produces red-green color blindness in men. A normal woman whose father was colorbling marries a colorblind man.
a What genotypes are possible for the mother of the colorblind man?
b What are the chances that the first child from this marriage will be a colorblind boy?
c Of all the girls produced by these parents, what percentage is expected to be color blind?
d Of all the children from these parents, what proportion is expected to be normal?
Biology
Principles of Inheritance & Variation (Genetics)In humans, hemophilia is a sex-linked recessive trait. A female who is a carrier for
hemophilia marries a male with normal blood clotting. If they do not know the gender
of their expected baby, determine the chance that the child will have hemophilia?
50%
0%
100%
Not enough information
25%
Biology
Principles of Inheritance & Variation (Genetics)For rock pocket mice, which of the following contributes to selective pressure favoring dark-colored fur? (select all that apply)
rock color
genetic mutations
predators
availability of food for the rock pocket mice
Biology
Principles of Inheritance & Variation (Genetics)When Watson and Crick were first proposing their model for DNA, they thought that
the nitrogenous bases paired like with like (ie adenine with adenine). This turned out
not to be feasible because
it would cause all base pairing to be the same in length.
the identical structure of the bases would not allow hydrogen bonding between them.
the sequence of bases in the molecules would be affected.
All of the above are correct.
Biology
Principles of Inheritance & Variation (Genetics)The male-specific region of the Y chromosome
lies between the two pseudoautosomal regions.
has regions called amplicons that include few palindromic sequences.
is completely identical to its counterparts on the X chromosome.
has an abundance of protein-encoding genes.
Biology
Principles of Inheritance & Variation (Genetics)In humans, having dimples in the cheeks is a dominant trait. If a child has dimples but
only one of her parents does, what are the genotypes of her parents? (D = dimples; d
= no dimples)
One parent dd, other parent DD
One parent dd, other parent Dd
One parent Dd, other parent DD
One parent must be DD, the other parent could be either dd or Dd
One parent must be dd, the other parent could be either Dd or DD
Biology
Principles of Inheritance & Variation (Genetics)The belief in the blending of traits was changed by Mendel's pea experiments. Mendel supported inheriting discrete.
A. alleles
B. DNA
C. genes
D. factors
Biology
Principles of Inheritance & Variation (Genetics)Two plants are crossed, resulting in offspring with a 3:1 ratio for a particular trait. What does this suggest?
that the trait shows incomplete dominance
that the parents were true-breeding for contrasting traits
that each offspring has the same alleles for each of two traits
that the parents were both heterozygous for a single trait
that a blending of traits has occurred
Biology
Principles of Inheritance & Variation (Genetics)For a species with a haploid number of 23 chromosomes, how many different combinations of maternal and paternal chromosomes are possible for the gametes?
920
46
460
23
about 8 million
Biology
Principles of Inheritance & Variation (Genetics)Peas were a good organism of choice for Mendel because
they cannot self-fertilize.
they cannot cross-fertilize.
the traits were difficult to visualize.
he could study one trait at a time.
Biology
Principles of Inheritance & Variation (Genetics)Which of the following did Mendel conclude about patterns of inheritance?
An organism inherits one gene from each parent.
The two genes of a given trait separate, or segregate, during gamete production.
Similar forms of genes account for variation in the inherited traits.
Organisms inherit one gene for each trait.
Biology
Principles of Inheritance & Variation (Genetics)In cats, an autosomal dominant mutation R causes a rounded ear shape. An
autosomal dominant mutation F causes feet with fewer toes.
A male cat Ff RR mates with a female cat that is Ff Rr.
What fraction of their offspring will have normal feet and rounded ears?
1/2
none of these
6/16
1/4
3/4
Biology
Principles of Inheritance & Variation (Genetics)Select the correct answer.
Jason adds the antibiotic penicillin to a bacterial culture. The bacteria develop genetic modifications in their genome, which gives them resistance to the antibiotic penicillin. What caused this genetic modification?
A mutations to the DNA sequence
B. normal gene regulation
C. operon gene induction
D. RNA interference
Biology
Principles of Inheritance & Variation (Genetics)2.One variety of strawberry is resistant to a damaging fungus, but produces small fruit. Another strawberry variety produces large fruit, but is not resistant to the same fungus. The two desirable qualities may be combined in a new variety of strawberry plant by
(1) cloning
(2) asexual reproduction
(3) direct harvesting
(4) selective breeding
Biology
Principles of Inheritance & Variation (Genetics)If all four heart valves are closed and the ventricular myocardium (heart muscle) is contracting the phase of the
cardiac cycle is
Diastole: sovolumetric contraction
Systole, Isovolumetric contraction
Diastole: Isovolumetric relaxation
Systole. Isovolumetric relaxation
Biology
Principles of Inheritance & Variation (Genetics)Height exhibits simple dominance, but petal
color is incompletely dominant in xenon plants.
If T= tall, t= dwarf, R= red, r= white, which
genotype(s) would most likely express color
other than white or red?
A
TTRr and
TtRr
B
ttrr and
TTRR
C
TtRR
only
Biology
Principles of Inheritance & Variation (Genetics)TT x tt
All of the offspring in the F1 generation of the
above cross would have the
genotype.
A
tt
B
TT
C
Tt
Biology
Principles of Inheritance & Variation (Genetics)RRYY x rryy
What potential gametes can be produced by the
dihybrid cross shown above?
A. RY, RY
B. Rr, Yy
C. RY, ry