Principles of Inheritance & Variation (Genetics) Questions and Answers
Biology
Principles of Inheritance & Variation (Genetics)Scientists cross two heterozygous pea plants with purple flowers together. The purple allele (A) is completely dominant and the white allele (a) is recessive. What is the
probability the offspring will will have the purple flower phenotype.
(You may use scratch paper to work out the problem)
0%
25%
75%
100%
50%
Biology
Principles of Inheritance & Variation (Genetics)A single clone of interest can be distinguished from others in a mixture of clones by
testing the clones for antibiotic resistance.
mobility of the clones in gel electrophoresis.
a specific probe, usually a labeled complementary DNA.
resistance to damage by ultraviolet light.
Biology
Principles of Inheritance & Variation (Genetics)In the 1950s, the scientists Alfred Hershey and Martha Chase carried out an experiment using
bacteriophages, which are viruses that infect bacteria. During the experiment, the scientists allowed
bacteriophages that had been labeled with a radioactive element to infect bacterial cells.
After carrying out their experiment, the scientists concluded that bacteriophages inject DNA (a type of nucleic acid), but not protein, into host bacterial cells during infection.
To be able to form this conclusion, which of the following radioactive elements did Hershey and Chase most likely find inside infected bacterial cells?
Choose 1 answer:
Radioactive hydrogen
Radioactive phosphorus
Radioactive carbon
Radioactive sulfur
Biology
Principles of Inheritance & Variation (Genetics)In some flowers, there are two alleles for color, and these can both be expressed equally at the same time. Which best describes this trait?
A. Dominant.
B. Sex-linked.
C. Codominant.
D. Asexual.
Biology
Principles of Inheritance & Variation (Genetics)Mr. (aa) and Mrs. Johnson (AA) have a child named Joe. What is Joe's genotype?
aa
AA
AAA
Aa
Biology
Principles of Inheritance & Variation (Genetics)A scientist is breeding flowers. They select a heterozygous individual with a dominant phenotype. A is completely dominant, and a is recessive. What is the possible genotype(s) of this flower?
Aa
aa
BAA
Biology
Principles of Inheritance & Variation (Genetics)You've discovered a deletion mutant of E. coli that cannot induce transcription of the lac system under any circumstances. Which of the following deletions could cause this phenotype?
Deletion of the promoter
Deletion of the operator
Deletion of the repressor gene
Deletion of one of the structural genes
Biology
Principles of Inheritance & Variation (Genetics)In the lab simulation, given that BB moths are black, bb moths are white, & Bb moths are grey, what type of genetic DOMINANCE is operating between the two alleles that code for the protein pigments that determine moth coloration?
partial dominance
incomplete dominance
complete dominance
codominance
None of the above.
Biology
Principles of Inheritance & Variation (Genetics)The DNA of a mouse is analyzed to reveal the presence of alleles resulting in brown fur color. The mouse is heterozygous, Bb, yet is completely colorless in phenotype. This can be explained as an occurrence of
(A) epigenesis.
(B) epistasis.
(C) incomplete dominance.
(D) pleiotropy.
(E) codominance.
Biology
Principles of Inheritance & Variation (Genetics)Following the Lederberg experiment, a scientist plated E. coli cells onto an agar plate with rich media and 125 colonies grew on this master plate. The scientist then replica printed the 125 colonies from the master plate onto two agar plates containing rich media plus the antibiotic kanamycin, which is known to kill E. coli cells. After an overnight incubation, the scientist observed a few antibiotic resistant mutant colonies growing on the same spots when comparing the two replica plates. What would explain these results?
Some cells acquired antibiotic resistant mutations after they were grown in the presence of the antibiotic.
All of the 125 colonies were antibiotic resistant before they were grown in the presence of the antibiotic.
Some resistant mutants were present within the population of 125 colonies before they were grown in the presence of the antibiotic.
Biology
Principles of Inheritance & Variation (Genetics)13. In hamsters, the CW allele produces a white-coat color phenotype. C is the wildtype allele and results in an orange coat color. A cross between a homozygous orange hamster with a white hamster results in 1:1 phenotype ratio of orange:white coat color in the progeny What can you conclude from this?
A) orange fur color is dominant to white fur color
B) the white parent is heterozygous
C) the C gene is haplosufficient
D) the C gene is temperature sensitive
E) A and B
Biology
Principles of Inheritance & Variation (Genetics)Which is true about mutations?
A. They are always beneficial.
B. They are always harmful.
C. They are mostly neutral and unnoticed.
D. They are always either beneficial or harmful.
Biology
Principles of Inheritance & Variation (Genetics)How do we know that alleles actually separate during gamete formation?
A. Scientists are unsure whether the alleles separate.
B. If the alleles did not separate, recessive alleles would never reappear.
C. Zygotes will not reach maturity if the alleles do not separate.
Biology
Principles of Inheritance & Variation (Genetics)Assume brown eyes (B) are dominant to blue (b). A brown-eyed man marries a blue-eyed woman. They have three children, two of whom are brown- eyed and one of whom is blue-eyed. Draw the Punnett square that illustrates this family. What is the man's genotype? What are the genotypes of the children?
Biology
Principles of Inheritance & Variation (Genetics)In pea plants, the trait for yellow seeds (Y) is dominant to that for green seeds (y). If a plant that is heterozygous for seed color is crossed with a plant that has green seeds, what are the expected genotypes of the offspring?
Yy and yy in a ratio of 1:1
Yellow and green in a ratio of 3:1
Yellow and green in a ratio of 1:1
YY, Yy, and yy in a ratio of 1:2:1
Biology
Principles of Inheritance & Variation (Genetics)What is the most important difference between nuclear DNA and mitochondrial
DNA?
Mitochondrial DNA does not use the same replication machinery as nuclear DNA
There is no difference
Mitochondrial DNA is inherited via ovum, whereas nuclear DNA comes from the ovum and the sperm
Mitochondrial DNA is single-stranded and nuclear DNA is double-stranded
Biology
Principles of Inheritance & Variation (Genetics)A plant that was homozygous recessive for seed shape and color was crossed with a plant that was heterozygous for seed shape. What percentage of the F1 generation will be heterozygous?
RR: Round seeds
Rr: Round seeds
rr: Wrinkled seeds
Biology
Principles of Inheritance & Variation (Genetics)Refer to #3b. A woman with sickle cell disease has children with a man who has sickle cell trait. What is the genetic makeup of the gametes the mother can produce?
SS
A
S
AA
AS
Biology
Principles of Inheritance & Variation (Genetics)1) For the scenario below, indicate which of the following "phenomena" is at work. More than one may
apply.
Co-Dominance - Epistasis - Incomplete Dominance - Pleiotropy - Polygenetic
2) Explain how you came to your answer.
3) Explain how/why the inheritance pattern differs from classic Mendelian inheritance.
Jane is the child of 2 people who both have very dark skin, dark brown eyes and black hair. The skin, hair and eye coloring of Jane's 4 siblings very closely match her parents. Jane has albinism, a recessive
condition that blocks the formation of the pigments associated with skin, hair and eye coloration.
Biology
Principles of Inheritance & Variation (Genetics)Holandric genes are carried on the Y chromosome in men and have no analogous genes in women. A holandric gene is known in men, which causes long hair to grow on the external ears. When men with hairy ears marry normal women:
a What percentage of their sons would be expected to have hairy eye?
b What proportions of the daughters is expected to show the trait?
c What ratio of hairy-eared:normal children is expected?
Biology
Principles of Inheritance & Variation (Genetics)Variations in the ___ sequence of a gene can affect how quickly the encoded protein is synthesized.
triplet
palindrome
promoter
terminator
anticodon
Biology
Principles of Inheritance & Variation (Genetics)In watermelon, the allele for green rinds is completely dominant to the allele for striped rinds. You are given a melon with a green rind and asked to establish a pure-breeding line. How would you proceed?
Biology
Principles of Inheritance & Variation (Genetics)The following parts of natural selection will be used to answer the next 4 questions.
A. Differential Reproduction
B. Overproduction
C. Struggle to Survive
D. Genetic Variation
Which part of natural selection (see choices above) is described by the following sentence:
More offspring can be produced than can survive to maturity.
Biology
Principles of Inheritance & Variation (Genetics)Several answers can be correct. If this is the case you
will need to check all the correct answers.
A trait or a character
a. is described by a word, either a noun or an
adjective
b. can be a physical characteristic, such as eye
color
c. is the expression of one or more genes
d. is described by a letter, either a capital letter or a
lowercase letter
e. is known as the genotype
Biology
Principles of Inheritance & Variation (Genetics)If the first child of the parents in problem 5 is feeble-minded, what is the probability that the second child will be feeble-minded? (This is akin to asking the question, if on a throw of the die, I threw a six, what is the probability that I will throw a 6 the second time? Note that this is a different question that what is the probability of throwing two 6's with two throws of the die.)
Biology
Principles of Inheritance & Variation (Genetics)What will be the genotype(s) of the F, generation from the following parents? In what ratios? (Hint: first determine the types of gametes each parent can form, and then combine all the different types of gametes possible from one parent with all the different types of gametes possible from the other parent.)
a BBFF x bbff
b AaMM x AAmm
c GgHh x gghh
Biology
Principles of Inheritance & Variation (Genetics)Wood rats are medium sized rodents with lots of interesting behaviors. You may know of them as packrats. Let's assume that the trait of bringing home shiny objects (H) is controlled by a single locus gene and is dominant to the trait of carrying home only dull objects (h). Suppose two heterozygous individuals are crossed. How many of each genotype would be expected if only 4 offspring were produced?
Biology
Principles of Inheritance & Variation (Genetics)In dogs, dark coat color is dominant to albinism, and short-haired coat is dominant to long-haired coat.
a If a dog pure-breeding for dark, short-coat is crossed with an albino, long-haired dog, what genotypes and phenotypic ratios do you expect in their offspring?
b If the pups are raised and then allowed to mate amongst themselves, what genotypes and phenotypic ratios do you expect in the offspring?
Biology
Principles of Inheritance & Variation (Genetics)After transcription and before translation, eukaryotic mRNA is modified by adding
a cap of modified nucleotides and a poly-A tail.
an AUG at one end and a poly-U tail at the other.
tRNAs and amino acids.
amino acids and a poly-A tail.
Biology
Principles of Inheritance & Variation (Genetics)In Guinea pigs, black hair (B) is dominant over white (b), rough coat texture (R) is dominant over smooth (r), and short hair (S) is dominant over long hair (s). Assume these genes are on separate chromosomes.
a For a cross between a homozygous black, rough, short-haired Guinea pig and a white, smooth, long-haired one, what would the phenotype(s) of the offspring (F₁) be?
b If two of the F, offspring were crossed, what would be the probability of getting a black, rough, short-haired pig in the F₂ generation?
Biology
Principles of Inheritance & Variation (Genetics)A color blind male mates with woman who has normal vision. The woman has no history of colorblindness in her family.What percentage of their sons are expected to be colorblind?
A) 25%
B) 50%
C) 75%
D)100%
E) 0%
Biology
Principles of Inheritance & Variation (Genetics)Which organism that was the first to be used to relate the behavior of chromosomes during melosis to Mendel's principles of Segregation and Independent Assortment?
(A) Garden peas
(B) Summer squash
C) Drosophila
D Chickens
E) Sweet peas
Biology
Principles of Inheritance & Variation (Genetics)Two heterozygotes are mated in a monohybrid cross. What is the best description of the resultant offspring?
50% of offspring will have the dominant phenotype and 50% will have the recessive phenotype.
75% of offspring will have the recessive phenotype and 25% will have the dominant phenotype.
All offspring will have the recessive phenotype.
75% of offspring will have the dominant phenotype and 25% will have
Biology
Principles of Inheritance & Variation (Genetics)Where DNA replication occurs in animal cells
adenine
antiparallel
chainreaction
cytosine
deoxyribose
Franklin
helix
hydrogen
leading
nucleotide
nucleus
kazaki
polymerase
repair
semiconservative
Biology
Principles of Inheritance & Variation (Genetics)Please explain how type 4 collagen gene mutations result in appearance of proteins and blood cells in urine.
Biology
Principles of Inheritance & Variation (Genetics)In cats, black fur color is caused by an X-linked allele; the other allele at this locus causes orange color. The heterozygote is tortoiseshell, which has black and orange fur. What kinds of offspring would you expect from the cross of a black female and an orange male?
tortoiseshell females; black males
orange females; black males
tortoiseshell females; tortoiseshell males
orange females; orange males
black females; orange males
Biology
Principles of Inheritance & Variation (Genetics)Two linked genes studied by Professor Barrett's lab control style length in a plant with an epistatic interaction, where long-styled plants are homozygous ssmm, mid-styled plants require at least one dominant Mallele, while the short-styled phenotype shows dominant epistasis where at least one S allele leads to the S morph. A cross is performed between an inbred short-styled SSMM plant and an inbred long-styled plant, and the F1 generation is backcrossed to a long-styled plant. If the two genes are 3 cM apart, what proportion of the progeny will have the mid-styled phenotype?
A) 1.5%
B) 3%
C) 97%
D) 98.5%
Biology
Principles of Inheritance & Variation (Genetics)In pea plants, flowers can be purple (P) or white (p). In a field of peas, you count 13 plants with white flowers and 202 plants with purple flowers.
A. What is the value of q?
B. What is the value of p?
C. What is the frequency of heterozygous plants in the field?
D. Check your work, p²+2pq+q2-1 Are your numbers correct?
Biology
Principles of Inheritance & Variation (Genetics)Which is not a good example of incomplete dominance?
(A) A parent with red flowers and a aparent with white flowers produce a pink flower offspring.com
B A parent with curly hair and a parent with straight hair produce a child with wavy hair.p
C Two parents with green seed pods produce an offspring with green seed pods.
D A parent with black wool and a parent with white wool produce an offspring with gray wool. €
Biology
Principles of Inheritance & Variation (Genetics)Assume that person number 1 is homozygous for each trait and is male. Assume
that person number 128 is female. What would be the characteristics of children
born from a marriage between person number 1 and person number 128? Which
parent would they most closely resemble?
Biology
Principles of Inheritance & Variation (Genetics)Annette, an avid geneticist, crossed a male Siamese cat of genotype A/a; B/b; C/c; d/d; E/e with a female Siamese cat of genotype a/a; B/b; c/c; d/d; e/e. What is the probability of producing progeny with the mother's phenotypes at all loci? Assume independent assortment.
A) 1/8
B) 1/16
C) 1/32
D) 3/32
Biology
Principles of Inheritance & Variation (Genetics)6) A genetic map between three genes (A, B, and C) is shown below, where the degree of
interference is known to be 0.5. A cross is performed between two parental strains of
genotype AAbbCC and aaBBcc. If the F1 generation is then testcrossed to an aabbcc
individual, what fraction of the offspring will be AaBbCc?
A-------20 cM-------B-------40 cM--------C
A) 0.02
B) 0.04
C) 0.8
D) 0.96
Biology
Principles of Inheritance & Variation (Genetics)A gene in mice is known to show recessive lethality but also has dominant coat colour
effects, where the presence of one copy of a particular allele will result in a yellow coat
colour instead of the wild type black coat phenotype. A yellow coat-coloured mouse is
crossed to an inbred black coat-coloured mouse. If two yellow coat-coloured mice from
this cross are crossed to each other, what fraction of the offspring will have black coats?
A) 1/4
B) 1/3
C) 2/3
D) 3/4
Biology
Principles of Inheritance & Variation (Genetics)Evaluate the following statements, and select those that correctly apply to the properties of microscopes.
The degree of contrast between a specimen and its surroundings is enhanced by the
use of special stains and opening the iris diaphragm wide to allow in maximum light.
When observing specimens with the 100x lens, adding a drop of oil to the slide will
improve the resolving power; the image will be clear rather than blurry.
Light rays with shorter wavelengths enhance the ability to resolve objects that are
close together.
If oil is not used with the 100x lens, the image will be less bright, compared to
specimens observed with a drop of oil on the slide.
If the 40x high-powered lens is used to view a specimen in conjunction with a 10X
ocular, the total magnification of the specimen will be 50x.
Biology
Principles of Inheritance & Variation (Genetics)A type of rickets is a X-linked dominant trait. If a female with rickets and an unaffected
male have a daughter, what are the chances that the daughter will inherit this type of
rickets?
100%
50%
0%
25%
cannot be determined, as there is not enough information
Biology
Principles of Inheritance & Variation (Genetics)Red-green Color-blindness is sex-linked recessive. Two parents with normal color
vision have a color-blind child. Give the genotype of both parents.
XDXD and XDY
XDXd and XDXD
xDxd and XDy
xdxd and XDY
Biology
Principles of Inheritance & Variation (Genetics)Mrs. Smith has a baby named Jessica. She believes one of two men can be the father of her child. A paternity test is done and the results are shown above. Which of the 2 men is the father of baby Jessica?
Biology
Principles of Inheritance & Variation (Genetics)In his famous 1928 experiments, Griffith discovered the principle of transformation. He used strains of bacteria that killed mice () or ones that kept them alive (R). Which of the following experiments actually proved the transformation principle ?
Heat killed mixed with live R killed the mouse.
Heat killed S and heat killed R killed the mouse.
Heat killed R mixed with live the mouse.
Heat killed Skilled the mouse. Heat killed did not kill the mouse.
Biology
Principles of Inheritance & Variation (Genetics)What conclusions can you draw from comparing the two graphs on page 4 of the worksheet? (select all that apply)
In Arizona, there is no selective advantage to light- or dark-colored fur.
In New Mexico, there is a selective advantage to having dark-colored fur
In Arizona, different colored mice are equally fit and therefore equally likely to survive and reproduce.
The fur color that makes a mouse more fit in their environment are more likely to survive and reproduce.
Biology
Principles of Inheritance & Variation (Genetics)On page 4 of the worksheet, compare the two graphs, Mouse Population in New Mexico and Mouse Population in Arizona. What can
be determined by the data? (select all that apply)
The population of dark-colored mice in New Mexico is increasing
The population of light-colored mice in New Mexico is decreasing.
The population of light-colored mice in Arizona is decreasing.
The population of dark-colored mice in Arizona is increasing