Principles of Inheritance & Variation (Genetics) Questions and Answers

In Japanese quall, the allele for curly feathers (c) is recessive to the allele for smooth feathers (C). Which of the following best describes the offspring of quail parents that each have the genotype Cc?
A. All offspring are expected to have smooth feathers.
B. Most offspring are expected to have smooth feathers.
C. Most offspring are expected to have curly feathers.
D. All offspring are expected to have curly feathers.
Biology
Principles of Inheritance & Variation (Genetics)
In Japanese quall, the allele for curly feathers (c) is recessive to the allele for smooth feathers (C). Which of the following best describes the offspring of quail parents that each have the genotype Cc? A. All offspring are expected to have smooth feathers. B. Most offspring are expected to have smooth feathers. C. Most offspring are expected to have curly feathers. D. All offspring are expected to have curly feathers.
Erwin Chargaff is considered one of the pioneering scientists in the field of molecular biology. In one of his studies, Chargaff observed that a sample of human DNA contained approximately 30% adenine and 20% guanine. Based on DNA structure, what are the expected percentages of the other nitrogenous bases in the sample?
A. 40% thymine, 10% cytosine
B. 10% Thymine, 40% cytosine
C. 30% thymine, 20% cytosine
D. 20% thymine, 30% cytosine
Biology
Principles of Inheritance & Variation (Genetics)
Erwin Chargaff is considered one of the pioneering scientists in the field of molecular biology. In one of his studies, Chargaff observed that a sample of human DNA contained approximately 30% adenine and 20% guanine. Based on DNA structure, what are the expected percentages of the other nitrogenous bases in the sample? A. 40% thymine, 10% cytosine B. 10% Thymine, 40% cytosine C. 30% thymine, 20% cytosine D. 20% thymine, 30% cytosine
A student was studying the two types of nucleic acid. Based on his observation, a piece of nucleic acid had the: 5'-GCUA-3' What kind of nucleic acid is this?
A. DNA
B. Protein
C. Unable to determine from this information
D. RNA
Biology
Principles of Inheritance & Variation (Genetics)
A student was studying the two types of nucleic acid. Based on his observation, a piece of nucleic acid had the: 5'-GCUA-3' What kind of nucleic acid is this? A. DNA B. Protein C. Unable to determine from this information D. RNA
A genotype is heterozygous if it has two different alleles. For example, Tt is
heterozygous. A genotype is homozygous if it has two of the same alleles.
For example, SS is homozygous.
Biology
Principles of Inheritance & Variation (Genetics)
A genotype is heterozygous if it has two different alleles. For example, Tt is heterozygous. A genotype is homozygous if it has two of the same alleles. For example, SS is homozygous.
A)
Examine the two strands of DNA below. Which kind of mutation occurred?
Original strand: AGC GTA CCC TAC
New strand: AGC GTA ACC TAC
(1 point)
substitution
insertion
frameshift
deletion
Biology
Principles of Inheritance & Variation (Genetics)
A) Examine the two strands of DNA below. Which kind of mutation occurred? Original strand: AGC GTA CCC TAC New strand: AGC GTA ACC TAC (1 point) substitution insertion frameshift deletion
A) What is heredity? 
the random distribution of chromosomes to produce new genetic combinations
the exchange of genetic information to create new variation
the adaptation of certain individuals that increases their likelihood of survival
the passing of genetic information from parents to their offspring
Biology
Principles of Inheritance & Variation (Genetics)
A) What is heredity? the random distribution of chromosomes to produce new genetic combinations the exchange of genetic information to create new variation the adaptation of certain individuals that increases their likelihood of survival the passing of genetic information from parents to their offspring
Q7: To further study gene regulation in the ara operon, you engineered a mutant bacterium in
which the araC gene has been deleted and then observed the effect of adding arabinose on
transcription of the mutant bacterium ara operon. Would you expect transcription to be high or
low in the presence of arabinose? Briefly explain. (2 marks)
Biology
Principles of Inheritance & Variation (Genetics)
Q7: To further study gene regulation in the ara operon, you engineered a mutant bacterium in which the araC gene has been deleted and then observed the effect of adding arabinose on transcription of the mutant bacterium ara operon. Would you expect transcription to be high or low in the presence of arabinose? Briefly explain. (2 marks)
Short hair on a cat is considered DOMINANT (you can use any letter but be sure you capitalize it for
the dominant allele and use lower case for recessive allele).
What genotypes are possible for a short-haired cat?
aa only
AA, Aa, and aa
aa and AA only
AA only
Aa and AA only
Biology
Principles of Inheritance & Variation (Genetics)
Short hair on a cat is considered DOMINANT (you can use any letter but be sure you capitalize it for the dominant allele and use lower case for recessive allele). What genotypes are possible for a short-haired cat? aa only AA, Aa, and aa aa and AA only AA only Aa and AA only
In the LGBTQIA+ abbreviation, "I" stands for the the Intersex; pick and briefly explain another term from this abbreviation that deals with sex/gender identity (but not sexual orientation- it's the whole other topic).
Biology
Principles of Inheritance & Variation (Genetics)
In the LGBTQIA+ abbreviation, "I" stands for the the Intersex; pick and briefly explain another term from this abbreviation that deals with sex/gender identity (but not sexual orientation- it's the whole other topic).
Which evidence best supports the claim that mutations are a source of inheritable genetic variation?
(1 point)
Mutations affect protein synthesis which impacts the way traits are expressed.
Mutations can only happen during meiosis because genes are inherited.
Mutations affect the way DNA is created through transcription.
Mutations are not inheritable from gametes because they are given from each parent.
Biology
Principles of Inheritance & Variation (Genetics)
Which evidence best supports the claim that mutations are a source of inheritable genetic variation? (1 point) Mutations affect protein synthesis which impacts the way traits are expressed. Mutations can only happen during meiosis because genes are inherited. Mutations affect the way DNA is created through transcription. Mutations are not inheritable from gametes because they are given from each parent.
Note: Blood type is controlled by 3 alleles of gene I: I^, P and i, Both alleles and I are dominant to allele I and are co-dominant to each other
a) What are the two genotypes possible for a person who as A blood?
b) What genotype does a person with AB blood have?
c)What genotype does a person with O blood have?
d) What are the two genotypes possible for a person who as B blood?
Biology
Principles of Inheritance & Variation (Genetics)
Note: Blood type is controlled by 3 alleles of gene I: I^, P and i, Both alleles and I are dominant to allele I and are co-dominant to each other a) What are the two genotypes possible for a person who as A blood? b) What genotype does a person with AB blood have? c)What genotype does a person with O blood have? d) What are the two genotypes possible for a person who as B blood?
A) During meiosis, sister chromatids may exchange sections of DNA leading to genetic
diversity. What is this process called? (1 point)
independent assortment
karyotypes
crossing-over
nondisjunction
Biology
Principles of Inheritance & Variation (Genetics)
A) During meiosis, sister chromatids may exchange sections of DNA leading to genetic diversity. What is this process called? (1 point) independent assortment karyotypes crossing-over nondisjunction
2. A male rabbit with the genotype GGbb is crossed with a female rabbit with the genotype ggBb. The square is set up below. Fill it out and determine the phenotypes and proportions in the offspring.
How many out of 16 have grey fur and black eyes?
How many out of 16 have grey fur and red eyes?
How many out of 16 have white fur and black eyes?
How many out of 16 have white fur and red eyes?
Biology
Principles of Inheritance & Variation (Genetics)
2. A male rabbit with the genotype GGbb is crossed with a female rabbit with the genotype ggBb. The square is set up below. Fill it out and determine the phenotypes and proportions in the offspring. How many out of 16 have grey fur and black eyes? How many out of 16 have grey fur and red eyes? How many out of 16 have white fur and black eyes? How many out of 16 have white fur and red eyes?
Gregor Mendel examined simple patterns of inheritance in his work with pea plants. Unlike pea plants, many human traits have complex patterns of inheritance. For example, some traits are controlled by several genes together. What is a trait that probably has a complex pattern of inheritance? Explain your response.
Biology
Principles of Inheritance & Variation (Genetics)
Gregor Mendel examined simple patterns of inheritance in his work with pea plants. Unlike pea plants, many human traits have complex patterns of inheritance. For example, some traits are controlled by several genes together. What is a trait that probably has a complex pattern of inheritance? Explain your response.
What type of glycosidic linkages are broken by the enzyme glycogen phosphorylase during glycogen degradation?
beta-1,6 linkages
alpha-1,4 linkages
alpha-1,6 linkages
beta-1,4 linkages
Biology
Principles of Inheritance & Variation (Genetics)
What type of glycosidic linkages are broken by the enzyme glycogen phosphorylase during glycogen degradation? beta-1,6 linkages alpha-1,4 linkages alpha-1,6 linkages beta-1,4 linkages
Flower color in snapdragons is controlled by incomplete dominance. Regarding the gene for flower color, there are two alleles CR and CW. Heterozygotes have pink flowers, whereas the two homozygotes have red flowers or white flowers. When plants with red flowers are crossed with plants with pink flowers, what proportion of the offspring is expected to have pink flowers?
Biology
Principles of Inheritance & Variation (Genetics)
Flower color in snapdragons is controlled by incomplete dominance. Regarding the gene for flower color, there are two alleles CR and CW. Heterozygotes have pink flowers, whereas the two homozygotes have red flowers or white flowers. When plants with red flowers are crossed with plants with pink flowers, what proportion of the offspring is expected to have pink flowers?
In cattle, an autosomal mutation called Dexter produces calves with short stature
and short limbs. Embryos that are homozygous for the Dexter mutations have
severely stunted development and either spontaneously abort or are still-born.
What are the expected proportions and phenotypes of the viable progeny if you
cross two Dexter cows?
3/4 Dexter : 1/4 normal
2/3 Dexter: 1/3 normal
1/2 Dexter : 1/2 normal
3/4 normal: 1/4 Dexter
1/3 Dexter: 2/3 normal
Biology
Principles of Inheritance & Variation (Genetics)
In cattle, an autosomal mutation called Dexter produces calves with short stature and short limbs. Embryos that are homozygous for the Dexter mutations have severely stunted development and either spontaneously abort or are still-born. What are the expected proportions and phenotypes of the viable progeny if you cross two Dexter cows? 3/4 Dexter : 1/4 normal 2/3 Dexter: 1/3 normal 1/2 Dexter : 1/2 normal 3/4 normal: 1/4 Dexter 1/3 Dexter: 2/3 normal
Use the FOIL method to determine the genes for the gametes that would go
on the outside of a punnett square in a dihybrid cross. Do this for one parent with
this genotype "EeGG". What are the 4 gene combinations for the gametes? *
EG, EG, eG, eG
EE, ee, GG, GG
Biology
Principles of Inheritance & Variation (Genetics)
Use the FOIL method to determine the genes for the gametes that would go on the outside of a punnett square in a dihybrid cross. Do this for one parent with this genotype "EeGG". What are the 4 gene combinations for the gametes? * EG, EG, eG, eG EE, ee, GG, GG
You are replicating Gregor Mendel's famous experiment with sweet peas. The genotype for dominant smooth-seeded parent is designated AA, while the genotype for the wrinkled-seeded parent is aa. Using a punnet square predict the first generation for this cross. What are the genotypic and phenotypic ratios? SHOW ALL WORK.
Biology
Principles of Inheritance & Variation (Genetics)
You are replicating Gregor Mendel's famous experiment with sweet peas. The genotype for dominant smooth-seeded parent is designated AA, while the genotype for the wrinkled-seeded parent is aa. Using a punnet square predict the first generation for this cross. What are the genotypic and phenotypic ratios? SHOW ALL WORK.
What must be true for an XX female to express a recessive sex-linked trait?
a X chromosome inactivation
b a Y chromosome
c two recessive alleles for the trait
d two dominant alleles for the trait
Biology
Principles of Inheritance & Variation (Genetics)
What must be true for an XX female to express a recessive sex-linked trait? a X chromosome inactivation b a Y chromosome c two recessive alleles for the trait d two dominant alleles for the trait
According to Mendel's law of segregation,
a. when two different alleles occur together one allele is complete expressed the other is hidden.
b. organisms donate only one copy of each gene in their gametes.
c. different alleles of a gene can never be found in the same organism.
d. genes for more than one trait are located on different chromosomes.
Biology
Principles of Inheritance & Variation (Genetics)
According to Mendel's law of segregation, a. when two different alleles occur together one allele is complete expressed the other is hidden. b. organisms donate only one copy of each gene in their gametes. c. different alleles of a gene can never be found in the same organism. d. genes for more than one trait are located on different chromosomes.
You are interested in tracking inheritance of a suite of traits in the blue-footed booby (Sula
nebouxii), a bird that is native to Pacific Coast of North, Central, and South America. You
cross a male with the genotype AAbbCcDd with a female with genotype aabbCcDd. What is
the expected probability of each of the following scenarios? Show all work to receive full
credit. (2 points each for 10 total points)
(a) chick that exhibits a dominant phenotype at all four loci
(b) a chick that exhibits a phenotype like its father
(c) a chick that exhibits a phenotype like its mother
(d) a chick that exhibits a dominant phenotype at the first three loci, and a recessive
phenotype for the last one
(e) a chick that exhibits a recessive phenotype at all four loci
Biology
Principles of Inheritance & Variation (Genetics)
You are interested in tracking inheritance of a suite of traits in the blue-footed booby (Sula nebouxii), a bird that is native to Pacific Coast of North, Central, and South America. You cross a male with the genotype AAbbCcDd with a female with genotype aabbCcDd. What is the expected probability of each of the following scenarios? Show all work to receive full credit. (2 points each for 10 total points) (a) chick that exhibits a dominant phenotype at all four loci (b) a chick that exhibits a phenotype like its father (c) a chick that exhibits a phenotype like its mother (d) a chick that exhibits a dominant phenotype at the first three loci, and a recessive phenotype for the last one (e) a chick that exhibits a recessive phenotype at all four loci
Having two eyebrows is dominant (E) over having one large eyebrow (e). Also having six
fingers (F) is dominant over having five fingers (f). What is the probability of each
phenotype if a man that has one eyebrow and twelve fingers total (heterozygous), has
children with a woman that is heterozygous for both traits?
Biology
Principles of Inheritance & Variation (Genetics)
Having two eyebrows is dominant (E) over having one large eyebrow (e). Also having six fingers (F) is dominant over having five fingers (f). What is the probability of each phenotype if a man that has one eyebrow and twelve fingers total (heterozygous), has children with a woman that is heterozygous for both traits?
(6.5) In the parental (P) generation, two purebred pea plants having contrasting forms for flower
color were cross-pollenated. After allowing the first filial (F₁) generation pea plants to self-
pollenate, 705 purple-flowering pea plants and 224 white-flowering pea plants were observed in
the second filial (F₂) generation.
What are the genotypes of the parental (P) pea plants?
a purple = PP and white = pp
b purple = P and white = p
c purple Pp and white = Pp
d purple Pp and white = pp
Biology
Principles of Inheritance & Variation (Genetics)
(6.5) In the parental (P) generation, two purebred pea plants having contrasting forms for flower color were cross-pollenated. After allowing the first filial (F₁) generation pea plants to self- pollenate, 705 purple-flowering pea plants and 224 white-flowering pea plants were observed in the second filial (F₂) generation. What are the genotypes of the parental (P) pea plants? a purple = PP and white = pp b purple = P and white = p c purple Pp and white = Pp d purple Pp and white = pp
In order to come to reliable conclusions about pillbug preferences, you needed to use the
Multiple Choice
modular data method.
experimental design method.
hypothetical method.
pretty graphs and charts.
scientific method.
Biology
Principles of Inheritance & Variation (Genetics)
In order to come to reliable conclusions about pillbug preferences, you needed to use the Multiple Choice modular data method. experimental design method. hypothetical method. pretty graphs and charts. scientific method.
(6.5) A fish farmer produces rainbow trout for stocking by private land owners and fishing clubs.
His particular breed of trout occur in two different phenotypes; black and gold. The farmer
knows the black trait is recessive in rainbow trout. When performing a test cross, the farmer
crosses a gold individual with an unknown genotype with several recessive individuals. From this
cross the farmer observes the gold phenotype in all 140 offspirng. What is the most likely
genotype of the offspring?
c purebreds
b homozygous dominant
c heterozygous dominant
d homozygous recessive
Biology
Principles of Inheritance & Variation (Genetics)
(6.5) A fish farmer produces rainbow trout for stocking by private land owners and fishing clubs. His particular breed of trout occur in two different phenotypes; black and gold. The farmer knows the black trait is recessive in rainbow trout. When performing a test cross, the farmer crosses a gold individual with an unknown genotype with several recessive individuals. From this cross the farmer observes the gold phenotype in all 140 offspirng. What is the most likely genotype of the offspring? c purebreds b homozygous dominant c heterozygous dominant d homozygous recessive
A segment of DNA which provides the instructions for making a protein is called a(n):
plasmid
chromosome
gene
mRNA
none of the above
Biology
Principles of Inheritance & Variation (Genetics)
A segment of DNA which provides the instructions for making a protein is called a(n): plasmid chromosome gene mRNA none of the above
A group of scientists are studying the genome of the Drosophila Fly. In these flies, the allele for long wings is dominant over the allele for short wings. What phenotype would a heterozygous genotype have?
A. LL
B. Long wings
C. Short wings
D. LI
Biology
Principles of Inheritance & Variation (Genetics)
A group of scientists are studying the genome of the Drosophila Fly. In these flies, the allele for long wings is dominant over the allele for short wings. What phenotype would a heterozygous genotype have? A. LL B. Long wings C. Short wings D. LI
You are a clinical geneticist and have a patient that is phenotypically female and has some developmental delays and a history of a congenital heart defect. To begin your diagnosis, you perform a Barr body test and find that the patient has no Barr bodies. What genetic condition is this patient likely to have? 
a. Edward's syndrome
b. Klinefelter syndrome
c. Patau Syndrome
d. Unable to determine with the given information.
e. Turner Syndrome
Biology
Principles of Inheritance & Variation (Genetics)
You are a clinical geneticist and have a patient that is phenotypically female and has some developmental delays and a history of a congenital heart defect. To begin your diagnosis, you perform a Barr body test and find that the patient has no Barr bodies. What genetic condition is this patient likely to have? a. Edward's syndrome b. Klinefelter syndrome c. Patau Syndrome d. Unable to determine with the given information. e. Turner Syndrome
For the mating below, indicate whether nondisjunction occurred in the mother, father, both or cannot be determined:
XBA xba x xba y-> xba xba y
a. Cannot be determined
b. Father
C. Both
d. Mother
Biology
Principles of Inheritance & Variation (Genetics)
For the mating below, indicate whether nondisjunction occurred in the mother, father, both or cannot be determined: XBA xba x xba y-> xba xba y a. Cannot be determined b. Father C. Both d. Mother
In pea plants Red (R) flower color is dominant over white (r) flower color and green seeds (G) are dominant over yellow seeds (g). (7)

A farmer has a pea plant with red flowers and green seeds What are the possible genotypes of this
plant?
He crossed this plant with another plant that has white flowers with yellow seeds. Genotype of this
plant is              . Such a cross is called
He obtained 5500 plants. 1400 of the off springs had red flowers with green seed and the 1385 of them had red flowers with yellow seeds and 1375 of the off springs had white flowers with green seeds and 1340 had white flowers with yellow seeds. What is the genotype of the pea plant that the farmer had?
Explain your results with Punnett square?
Biology
Principles of Inheritance & Variation (Genetics)
In pea plants Red (R) flower color is dominant over white (r) flower color and green seeds (G) are dominant over yellow seeds (g). (7) A farmer has a pea plant with red flowers and green seeds What are the possible genotypes of this plant? He crossed this plant with another plant that has white flowers with yellow seeds. Genotype of this plant is . Such a cross is called He obtained 5500 plants. 1400 of the off springs had red flowers with green seed and the 1385 of them had red flowers with yellow seeds and 1375 of the off springs had white flowers with green seeds and 1340 had white flowers with yellow seeds. What is the genotype of the pea plant that the farmer had? Explain your results with Punnett square?
Approximately where is gene a located along the chromosome?
about one-third of the distance from the maroon-eye locus to the black-body locus
about two-thirds of the distance from the maroon-eye locus to the cinnabar-eye locus
about two-thirds of the distance from the maroon-eye locus to the vestigial-wing locus locus
equidistant between the maroon-eye locus to the cinnabar-eye locus
Biology
Principles of Inheritance & Variation (Genetics)
Approximately where is gene a located along the chromosome? about one-third of the distance from the maroon-eye locus to the black-body locus about two-thirds of the distance from the maroon-eye locus to the cinnabar-eye locus about two-thirds of the distance from the maroon-eye locus to the vestigial-wing locus locus equidistant between the maroon-eye locus to the cinnabar-eye locus
What protein usually helps RNA polymerase to bind to a promoter?
a. Activator O b. Corepressor O c. Terminator O d. Repressor
Biology
Principles of Inheritance & Variation (Genetics)
What protein usually helps RNA polymerase to bind to a promoter? a. Activator O b. Corepressor O c. Terminator O d. Repressor
The most important factor determining the direction and strength of sexual selection is:
Offspring size
O Offspring relatedness
Inbreeding coefficient
Parental investment
Biology
Principles of Inheritance & Variation (Genetics)
The most important factor determining the direction and strength of sexual selection is: Offspring size O Offspring relatedness Inbreeding coefficient Parental investment
You perform a cross between two plants, one MmPp and one mmpp, and obtain offspring with the following phenotypes: 42 MP; 374 Mp; 367 mP; 27 mp. What can you conclude from these data?
ONLY PICK ONE OF THE ANSWERS:
A. The M and P genes are on different chromosomes
B. The recombinant progeny are mP and Mp
C. The M and P genes are far apart on the same chromosome
D. The recombinant progeny are MP and mp
Biology
Principles of Inheritance & Variation (Genetics)
You perform a cross between two plants, one MmPp and one mmpp, and obtain offspring with the following phenotypes: 42 MP; 374 Mp; 367 mP; 27 mp. What can you conclude from these data? ONLY PICK ONE OF THE ANSWERS: A. The M and P genes are on different chromosomes B. The recombinant progeny are mP and Mp C. The M and P genes are far apart on the same chromosome D. The recombinant progeny are MP and mp
Fill in the space__ repeats are structural motifs found in many proteins, and they consist of a hairpin loop followed by a helix-turn-helix.
Biology
Principles of Inheritance & Variation (Genetics)
Fill in the space__ repeats are structural motifs found in many proteins, and they consist of a hairpin loop followed by a helix-turn-helix.
Northern blot hybridization is based on:
A. DNA and RNA.
B. DNA and DNA.
C. RNA and lipid.
D. RNA and protein
Biology
Principles of Inheritance & Variation (Genetics)
Northern blot hybridization is based on: A. DNA and RNA. B. DNA and DNA. C. RNA and lipid. D. RNA and protein
In cocker spaniels, solid color (A) is dominant over spotted (a), and black coat color (B)
is dominant over red (b). If a solid red male was crossed with a solid black female to
produce a spotted red puppy, the genotypes of the parents (with male first) would be
aa bb x Aa Bb
AA bb x AA Bb
Aa Bb x Aa Bb
Aa bb x Aa Bb
Aa Bb x aa Bb
Biology
Principles of Inheritance & Variation (Genetics)
In cocker spaniels, solid color (A) is dominant over spotted (a), and black coat color (B) is dominant over red (b). If a solid red male was crossed with a solid black female to produce a spotted red puppy, the genotypes of the parents (with male first) would be aa bb x Aa Bb AA bb x AA Bb Aa Bb x Aa Bb Aa bb x Aa Bb Aa Bb x aa Bb
In Jimson weed, the allele for violet petals (A) is dominant over allele for white petals
(a). The allele for prickly capsules (B) is dominant over the allele for smooth capsules
(b). A plant with white petals and prickly capsules was crossed with one that had
violet petals and smooth capsules. The F1 generation had 47 white, prickly plants; 45
white smooth plants; 50 violet prickly plants, and 46 violet smooth plants. What
were the genotypes of the parents?
AA BB x aa bb
Aa bb x aa Bb
Aa Bb x Aa Bb
AA bb x aa BB
Biology
Principles of Inheritance & Variation (Genetics)
In Jimson weed, the allele for violet petals (A) is dominant over allele for white petals (a). The allele for prickly capsules (B) is dominant over the allele for smooth capsules (b). A plant with white petals and prickly capsules was crossed with one that had violet petals and smooth capsules. The F1 generation had 47 white, prickly plants; 45 white smooth plants; 50 violet prickly plants, and 46 violet smooth plants. What were the genotypes of the parents? AA BB x aa bb Aa bb x aa Bb Aa Bb x Aa Bb AA bb x aa BB
In pea seeds, round (R) is dominant to wrinkled (r) and yellow (Y) is dominant to green (y). What percentage of round yellow seeds is expected from the cross: RrYY x RRYY?
O 50%
100%
0%
25%
75%
Biology
Principles of Inheritance & Variation (Genetics)
In pea seeds, round (R) is dominant to wrinkled (r) and yellow (Y) is dominant to green (y). What percentage of round yellow seeds is expected from the cross: RrYY x RRYY? O 50% 100% 0% 25% 75%
The color of chickens is determined by gene B, such that BB- black, Bb = gray, and bb = white. A second gene R controls comb shape, with dominant rose and recessive single comb. If a white single-combed chicken is mated with a gray chicken that is heterozygous for rose comb, what fraction of the offspring will be gray with rose comb? 
1/4 
1/16 
1/8 
9/16 
3/8
Biology
Principles of Inheritance & Variation (Genetics)
The color of chickens is determined by gene B, such that BB- black, Bb = gray, and bb = white. A second gene R controls comb shape, with dominant rose and recessive single comb. If a white single-combed chicken is mated with a gray chicken that is heterozygous for rose comb, what fraction of the offspring will be gray with rose comb? 1/4 1/16 1/8 9/16 3/8
Sickle cell anemia (SCA) is an autosomal recessive disorder. Doug has SCA, but his
wife is homozygous dominant. What is the chance that their child will have sickle cell
anemia?
0%
25%
50%
75%
100%
Biology
Principles of Inheritance & Variation (Genetics)
Sickle cell anemia (SCA) is an autosomal recessive disorder. Doug has SCA, but his wife is homozygous dominant. What is the chance that their child will have sickle cell anemia? 0% 25% 50% 75% 100%
Tay Sachs is a lysosomal storage disease that is inherited in an autosomal recessive manner. Individuals with Tay Sachs have a defect in the gene encoding hexosaminidase A, a lysosomal enzyme that breaks down cell membrane components called gangliosides. The inability to break down gangliosides causes harmful quantities of this lipid to accumulate in nerve cells of the brain, eventually leading to premature death of affected cells. There is no known cure for the disease, and death usually occurs by age 4. Jack and Jill have a child who has Tay-Sachs. What do you know about the genotypes of Jack and Jill? (T= dominant allele; t = recessive allele) offspring? O Both areheterozygous One is TT and the otheris tt Both are TT Both are tt O Its impossible to tell. Sinceboth are adults, they do not have the disease. But, they could either beTT or Tt
Biology
Principles of Inheritance & Variation (Genetics)
Tay Sachs is a lysosomal storage disease that is inherited in an autosomal recessive manner. Individuals with Tay Sachs have a defect in the gene encoding hexosaminidase A, a lysosomal enzyme that breaks down cell membrane components called gangliosides. The inability to break down gangliosides causes harmful quantities of this lipid to accumulate in nerve cells of the brain, eventually leading to premature death of affected cells. There is no known cure for the disease, and death usually occurs by age 4. Jack and Jill have a child who has Tay-Sachs. What do you know about the genotypes of Jack and Jill? (T= dominant allele; t = recessive allele) offspring? O Both areheterozygous One is TT and the otheris tt Both are TT Both are tt O Its impossible to tell. Sinceboth are adults, they do not have the disease. But, they could either beTT or Tt
In a Punnett square where are the gametes listed?
O In the boxes of the square
O Along the top and left side of the square
O On the bottom and right sides of the square
O On the left and right sides of the square
Biology
Principles of Inheritance & Variation (Genetics)
In a Punnett square where are the gametes listed? O In the boxes of the square O Along the top and left side of the square O On the bottom and right sides of the square O On the left and right sides of the square
If short hair (L) is dominant to long hair (1), then what fraction of the offspring produced by a cross of LI x II will be homozygous recessive? 
1/2
1/4
none of the answer choices are correct 
1/3
zero ( no chance of this offspring)
Biology
Principles of Inheritance & Variation (Genetics)
If short hair (L) is dominant to long hair (1), then what fraction of the offspring produced by a cross of LI x II will be homozygous recessive? 1/2 1/4 none of the answer choices are correct 1/3 zero ( no chance of this offspring)
In pea plants, the allele for tall (T) is dominant to the allele for short (t). The genotype
for a short pea plant is
Tt or tt
Tt
tt
TT or tt
Biology
Principles of Inheritance & Variation (Genetics)
In pea plants, the allele for tall (T) is dominant to the allele for short (t). The genotype for a short pea plant is Tt or tt Tt tt TT or tt
If a parent has genotype "Aa", then through normal meiosis, he would produce
gametes with
all gametes with only "A" allele
some gametes with "a" and some gametes with "A"
all gametes with only "a" allele
all gametes have both "Aa" alleles
Biology
Principles of Inheritance & Variation (Genetics)
If a parent has genotype "Aa", then through normal meiosis, he would produce gametes with all gametes with only "A" allele some gametes with "a" and some gametes with "A" all gametes with only "a" allele all gametes have both "Aa" alleles
Familial intestinal polyposis results in multiple fingerlike growths (polyps) from the
lining of the large intestine. Polyposis is inherited as a dominant trait (A). If both
parents are Aa and the couple has 16 children, how many would be expected to have
the familial intestinal polyposis phenotype?
0
8
16
04
12
Biology
Principles of Inheritance & Variation (Genetics)
Familial intestinal polyposis results in multiple fingerlike growths (polyps) from the lining of the large intestine. Polyposis is inherited as a dominant trait (A). If both parents are Aa and the couple has 16 children, how many would be expected to have the familial intestinal polyposis phenotype? 0 8 16 04 12
In guinea pigs, black is dominant over white. A black guinea pig would be
O homozygous recessive
O homozygous recessive or heterozygous
O homozygous dominant or heterozygous
O heterozygous
O homozygous dominant
Biology
Principles of Inheritance & Variation (Genetics)
In guinea pigs, black is dominant over white. A black guinea pig would be O homozygous recessive O homozygous recessive or heterozygous O homozygous dominant or heterozygous O heterozygous O homozygous dominant
Mendel's laws derive from
processes unique to pea plants.
mitosis.
calculus and algebra.
meiosis.
Biology
Principles of Inheritance & Variation (Genetics)
Mendel's laws derive from processes unique to pea plants. mitosis. calculus and algebra. meiosis.